Nick Mordwinkin > Biography

My research is focused on the biological mechanisms of adult stem cells, embryonic stem cells, and induced pluripotent stem cells, as well as developing regenerative medicine products targeting tissues damaged due to complications from diabetes. Our lab uses a combination of next generation sequencing, tissue engineering, physiological testing, and molecular imaging technologies to better understand stem cell biology in vitro and in vivo. For adult stem cells, we are interested in monitoring stem cell survival, proliferation, and differentiation. For embryonic stem cells, we are currently studying their tumorigenicity, immunogenicity, and differentiation into cardiomyocytes and endothelial cells. For induced pluripotent stem cells, we are interested in cadiovascular disease modeling, drug screening, and cell therapy. We also develop novel vectors and therapeutic genes for cardiovascular gene therapy applications.