Case number IPR2019-00170
Foundation Medicine, Inc. v. Caris MPI, Inc. > Documents
| Date Field | Doc. No. | Party | Description |
|---|---|---|---|
| Jan 10, 2020 | 3004 | Ex. 3004 Download | |
| Jul 22, 2019 | 3003 | Exhibit 3003 Download | |
| Jul 15, 2019 | 3002 | Exhibit 3002 Download | |
| Mar 14, 2019 | 3001 | Ex 3001 Download | |
| Mar 3, 2020 | 2076 | Patent Owner's Demonstratives Download | |
| Jan 23, 2020 | 2075 | Transcript of the Deposition of Paul T. Spellman, Volume II, January 15, 2020 Download | |
| Jan 23, 2020 | 2074 | Moulder, et al. Epidermal Growth Factor Receptor (HER1) Tyrosine Kinase Inhibitor ZD1839 (Iressa) Inhibits HER2/neu (erbB2) overexpressing Breast Cancer Cells in Vitro and In Vivo Download | |
| Jan 23, 2020 | 2073 | Nicholson, Modulation of Epidermal Growth Factor Receptor in Endocrine Resistant, Oestrogen Receptor Positive Breast Cancer Download | |
| Jan 23, 2020 | 2072 | Table A1 Pairings of Targets and Drugs Download | |
| Dec 5, 2019 | 2071 | Declaration of Jonathan Singer Download | |
| Oct 4, 2019 | 2070 | Declaration of Corrin Drakulich Download | |
| Oct 3, 2019 | 2069 | Declaration of Christina Brown-Marshall Download | |
| Sep 19, 2019 | 2068 | Deposition Transcript of Paul Spellman, Ph.D., Foundation Medicine V. Caris MPI, Inc. July 25, 2019 Download | |
| Sep 19, 2019 | 2067 | Ohta et al., ¿¿¿Fluorescence in Situ Hybridization Evaluation of c-erbB-2 Gene Amplification and Chromosomal Anomalies in Bladder Cancer,¿¿¿ Clinical Cancer Research, Vol. 7, Issue 9, pp. 2463-2467 Download | |
| Sep 19, 2019 | 2066 | Inokuchi et al., ¿¿¿Abnormality of C-Kit Oncoprotein in Certain Patients With Chronic Myelogenous Leukemia¿¿¿Potential Clinical Significance,¿¿¿ Leukemia 2002, pp. 170-177 Download | |
| Sep 19, 2019 | 2065 | Wisniewski et al., ¿¿¿Characterization of Potent Inhibitors of the Bcr-Abl and the c-Kit Receptor Tyrosine Kinases,¿¿¿ Cancer Research, Vol. 62, August 1, 2002, pp. 4244-4255 Download | |
| Sep 19, 2019 | 2064 | B. Ramanath Rao and Berend J. Slotman, ¿¿¿Endocrine Factors in Common Epithelial Ovarian Cancer,¿¿¿ Endocrine Reviews, Vol. 12, Issue 1, February 1, 1991, pp. 14-26 (Abstract) Download | |
| Sep 19, 2019 | 2063 | Zhou et al., ¿¿¿PTEN Mutational Spectra, Expression Levels, and Subcellular Localization in Microsatellite Stable and Unstable Colorectal Cancers,¿¿¿ American Journal of Pathology, Vol. 161, No. 2, August 2002, pp. 439-447 Download | |
| Sep 19, 2019 | 2062 | ¿¿¿A Culture Dedicated to Advancing Cancer Care,¿¿¿ downloaded from https://www.foundationmedicine.com/about Download | |
| Sep 19, 2019 | 2061 | ¿¿¿About Us: Fulfilling the Promise of Precision Medicine,¿¿¿ downloaded from https://www.carislifesciences.com/about/ on September 16, 2019 Download | |
| Sep 19, 2019 | 2060 | Adrienne Burke, ¿¿¿Foundation Medicine Personalizing Cancer Drugs,¿¿¿ MIT Technology Review, February 12, 2012, last accessed on September 16, 2019 at https://www.technologyreview.com/s/426987/foundation-medicine-personalizing-cancer-drugs/ Download | |
| Sep 19, 2019 | 2059 | Caris Life Sciences, Sample MiProfile Molecular Intelligence Tumor Report, downloaded from https://www.carismolecularintelligence.com/ Download | |
| Sep 19, 2019 | 2058 | FoundationOne Sample Report, downloaded from https://www.foundationmedicine.com Download | |
| Sep 19, 2019 | 2057 | National Comprehensive Cancer Network, ¿¿¿Breast Cancer Version 4.2017 Clinical Practice Guidelines in Oncology¿¿¿, Journal of the National Comprehensive Cancer Network, Vol. 16, No. 3, March 2018, pp. 310-320 Download | |
| Sep 19, 2019 | 2056 | Shi et al., ¿¿¿QA/QC: Challenges and Pitfalls Facing the Microarray Community and Regulatory Agencies, Expert Review of Molecular Diagnostics, Vol. 4, No. 6, (2004) pp. 761-777 Download | |
| Sep 19, 2019 | 2055 | Ahmed Ashour Ahmed and James D. Brenton, ¿¿¿Microarrays and Breast Cancer Clinical Studies: Forgetting We Have Not Yet Learnt,¿¿¿ Breast Cancer Research, Vol. 7, No. 3, May 2005, pp. 96-99 Download | |
| Sep 19, 2019 | 2054 | Joyce A. O¿¿¿Shaughnessy, ¿¿¿Molecular Signatures Predict Outcomes of Breast Cancer,¿¿¿ The New England Journal of Medicine,¿¿¿ Vol. 355, No. 6, August 10, 2006, pp. 615-617 Download | |
| Sep 19, 2019 | 2053 | Agoff et al., ¿¿¿Androgen Receptor Expression in Estrogen Receptor-Negative Breast Cancer. Immunohistochemical, Clinical, and Prognostic Associations,¿¿¿ American Journal of Clinical Pathology, Vol. 120, No. 5, November 2003 (Abstract) Download | |
| Sep 19, 2019 | 2052 | Cynthia A. Heinlein and Chawnshang Chang, ¿¿¿Androgen Receptor in Prostate Cancer,¿¿¿ Endocrine Reviews, Vol. 25, No. 2, April 2004, p. 276-308 Download | |
| Sep 19, 2019 | 2051 | Mace L. Rothenberg, ¿¿¿Irinotecan (CPT-11): ¿¿¿Recent Developments and Future Directions¿¿¿Colorectal Cancer and Beyond,¿¿¿ The Oncologist, pp. 66-80 Download | |
| Sep 19, 2019 | 2050 | Staker et al., ¿¿¿The Mechanism of Topoisomerase I Poisoning By a Camptothecin Analog,¿¿¿ PNAS, Vol. 99, No. 24, November 26, 2002, pp. 15387-15392 Download | |
| Sep 19, 2019 | 2049 | Rodriguez-Viciana et al., ¿¿¿Cancer Targets in the Ras Pathway,¿¿¿ Cold Spring Harbor Laboratory Press (2005), pp. 461-467 Download | |
| Sep 19, 2019 | 2048 | Kanaya et al., ¿¿¿Frequent Hypermethylation of MLH1 Promoter in Normal Endometrium of Patients with Endometrial Cancers,¿¿¿ Oncogene pp. 2352-2360 (2003) Download | |
| Sep 19, 2019 | 2047 | Luchtenborg et al., ¿¿¿Mutations ins APC, CTNNB1 and K-Ras Genes and Expression of hMLH1 in Sporadic Colorectal Carcinomas from the Netherlands Cohort Study,¿¿¿ BMC Cancer, December 15, 2005 Download | |
| Sep 19, 2019 | 2046 | Corless et al., ¿¿¿PDGFRA Mutations in Gastrointestinal Stromal Tumors: Frequency, Spectrum and In Vitro Sensitivity to Imatinib,¿¿¿ Journal of Clinical Oncology, Vol. 23, No. 23, August 10, 2005, pp. 5357-5364 Download | |
| Sep 19, 2019 | 2045 | DC Allred, ¿¿¿Origins of estrogen receptor alpha-positive and estrogen receptor alpha-negative human breast cancer,¿¿¿ Breast Cancer Research (2004) Download | |
| Sep 19, 2019 | 2044 | Haber et al., ¿¿¿Molecular Targeted Therapy of Lung Cancer: EGFR Mutations and Response to EGFR Inhibitors,¿¿¿ Cold Spring Harbor Laboratory Press, Vol. LXX, 2005, pp. 419-426 Download | |
| Sep 19, 2019 | 2043 | Fuerst, ¿¿¿Dan Von Hoff¿¿¿s Karnofsky Lecture: Smart Phase I Trials Can Extend Life Beyond ¿¿¿The Last 12 Weeks,¿¿¿¿¿¿ Oncology Times ASCO Meeting Reporter Supplement, August 10, 2010, pp. 21-23 Download | |
| Sep 19, 2019 | 2042 | Von Hoff et al., ¿¿¿Frequency of Potential Therapeutic Targets Identified by IHC and DNA Microarray in Tumors From Patients Who Have Progressed on Multiple Therapeutic Agents,¿¿¿ Journal of Clinical Oncology, Vol. 24, No. 18. Suppl.3, June 2006 Abstract Download | |
| Sep 19, 2019 | 2041 | Richard Simon, ¿¿¿Roadmap for Developing and Validating Therapeutically Relevant Genomic Classifiers,¿¿¿ Journal of Clinical Oncology, Vol. 23, No. 29, October 10, 2005, pp. 7332-7341 Download | |
| Sep 19, 2019 | 2040 | Flavell, ¿¿¿Keytruda,¿¿¿ Immuno-Oncology News, downloaded from the internet at https://immuno-oncologynews.com/keytruda-pembrolizumab/ on August 15, 2019, 8 pages Download | |
| Sep 19, 2019 | 2039 | National Comprehensive Cancer Network, ¿¿¿Gastric Cancer Clinical Practice Guidelines in Oncology¿¿¿, Journal of the National Comprehensive Cancer Network, Vol. 1, No. 1, January 2003, pp. 27-39 Download | |
| Sep 19, 2019 | 2038 | Tanner et. al, ¿¿¿Amplification of HER-2 in Gastric Carcinoma,¿¿¿ Annals of Oncology, Vol. 16, 2005, pp. 273-278 Download | |
| Sep 19, 2019 | 2037 | Kari et. al, ¿¿¿Targeting the Epidermal Growth Factor in Cancer,¿¿¿ Cancer Research, Vol. 63, January 1, 2003, pp. 1-5 Download | |
| Sep 19, 2019 | 2036 | Pao et al., ¿¿¿EGF receptor gene mutations are common in lung cancers from ¿¿¿never smokers¿¿¿ and correlate with sensitivity of tumors to gefitinib (Iressa) and erlotinib (Tarceva),¿¿¿ PNAS, Vol. 101, No. 36, September 7, 2004, pp. 13306-13311 Download | |
| Sep 19, 2019 | 2035 | Paez et al., ¿¿¿EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy,¿¿¿ Science, Vol. 304, June 4, 2004, pp. 1497-1500 Download | |
| Sep 19, 2019 | 2034 | Lynch et al., ¿¿¿Activating mutation in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib,¿¿¿ NEJM, Vol. 350, May 20, 2004, Abstract Download | |
| Sep 19, 2019 | 2033 | Shen et al., ¿¿¿Utilization Patterns and Trends in Epidermal Growth Factor Receptor (EGFR) Mutation Testing among Patients with Newly Diagnosed Metastatic Lung Cancer,¿¿¿ Clinical Lung Cancer, Vol. 18, No. 4, July 2017, pp. e233-e241 Download | |
| Sep 19, 2019 | 2032 | Avastin¿¿, Highlights of Prescribing Information downloaded from the internet at https://www.gene.com/download/pdf/avastin_prescribing.pdf on August 15, 2019, 39 pages Download | |
| Sep 19, 2019 | 2031 | Gleevec¿¿ Label, downloaded from https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=021335 on August 19, 2019, 22 pages Download | |
| Sep 19, 2019 | 2030 | Gleevec¿¿ FDA 2002 Approval Letter downloaded from https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=021335 on August 19, 2019, 4 pages Download | |
| Sep 19, 2019 | 2029 | Leslie A. Pray, ¿¿¿Gleevec¿¿: The Breakthrough in Cancer Treatment,¿¿¿ Nature Education, Vol. 1, 2008, 4 pages Download | |
| Sep 19, 2019 | 2028 | Gleevec¿¿ FDA 2001 Approval Letter downloaded from https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=021335 on August 19, 2019, 3 pages Download | |
| Sep 19, 2019 | 2027 | Lawrence et al., ¿¿¿Phase I Clinical Trial of Alitretinoin and Tamoxifen in Breast Cancer Patients: Toxicity, Pharmacokinetic, and Biomarker Evaluations,¿¿¿ Journal of Clinical Oncology, May 15, 2001, pp. 2754-2763 Download | |
| Sep 19, 2019 | 2026 | Corless et al., ¿¿¿Tackling Formalin-Fixed, Paraffin-Embedded Tumor Tissue with Next-Generation Sequencing,¿¿¿ Cancer Discovery, January 12, 2012, pp. 23-24 Download | |
| Sep 19, 2019 | 2025 | The Cancer Genome Atlas Research Network et al., ¿¿¿The Cancer Genome Atlas Pan-Cancer Analysis Project,¿¿¿ Nature Genetics, Vol. 45, No. 10, October 2013, pp. 1113-1120 Download | |
| Sep 19, 2019 | 2024 | National Comprehensive Cancer Network, ¿¿¿Colon Cancer Version 1.2017 Clinical Practice Guidelines in Oncology¿¿¿, Journal of the National Comprehensive Cancer Network, Vol. 15, No. 3, March 2017, pp. 370-398 Download | |
| Sep 19, 2019 | 2023 | Sorlie, et al., ¿¿¿Repeated Observation of Breast Tumor Subtypes in Independent Gene Expression Sets,¿¿¿ PNAS Vol. 100, No. 14, July 8, 2003, pp. 8418-8423. Download | |
| Sep 19, 2019 | 2022 | Hanahan, et al., ¿¿¿The Hallmarks of Cancer,¿¿¿ Cell, Vol. 100, 57-70, January 7, 2000 Download | |
| Sep 19, 2019 | 2021 | Expert Declaration of Joyce O¿¿¿Shaughnessy, M.D. Download | |
| Mar 6, 2019 | 2020 | File Excerpt of U.S. Patent No. 8,880,350 Download | |
| Mar 6, 2019 | 2019 | Foundation Medicine, Inc., Form 10-K, filed March 3, 2017 for the period ending December 31, 2016 Download | |
| Mar 6, 2019 | 2018 | Foundation Medicine, Inc., Foundation One Technical Information and Test Overview Download | |
| Mar 6, 2019 | 2017 | The Translational Genomics Research Institute, Dr. Daniel Von Hoff Presented with Top Genomics Award from Scripps Download | |
| Mar 6, 2019 | 2016 | Tamoxifen Prescribing Information Download | |
| Mar 6, 2019 | 2015 | Femara Prescribing Information Download | |
| Mar 6, 2019 | 2014 | Doroshow, et al. Selecting Systemic Cancer Therapy One Patient at a Time Download | |
| Mar 6, 2019 | 2013 | Von Hoff, Pilot Study Using Molecular Profiling of Patients Tumors to Find Potential Targets and Select Treatments for Their Refractory Cancers Download | |
| Mar 6, 2019 | 2012 | Seena Magowitz Foundation, Dr. Daniel Von Hoff Wins ASCO Award Download | |
| Mar 6, 2019 | 2011 | U.S. Patent No. 9,292,660 Download | |
| Mar 6, 2019 | 2010 | U.S. Patent No. 9,383,365 Download | |
| Mar 6, 2019 | 2009 | U.S. Patent No. 8,880,350 Download | |
| Mar 6, 2019 | 2008 | Declaration of Sandeep K. Reddy, submitted during prosecution of U.S. Patent App. 14/249,261 Download | |
| Mar 6, 2019 | 2007 | National Comprehensive Cancer Network, Colon Cancer Clinical Practice Guidelines in Oncology Download | |
| Mar 6, 2019 | 2006 | Leyland Jones, Trastuzumab: Hopes and Realities, The Lancet Oncology Download | |
| Mar 6, 2019 | 2005 | National Comprehensive Cancer Network, Breast Cancer Clinical Practice Guidelines in Oncology Download | |
| Mar 6, 2019 | 2004 | Benson, et al. American Society of Clinical Oncology Recommendations on Adjuvant Chemotherapy for Stage II Colon Cancer Download | |
| Mar 6, 2019 | 2003 | Declaration of Michael Castro, submitted during prosecution of U.S. Patent App. 11/750,721 Download | |
| Mar 6, 2019 | 2002 | Wakelee, et al. Optimizing First Line Treatment Options for Patience with Advanced NSCLC Download | |
| Mar 6, 2019 | 2001 | Horstmann, et al. Risks and Benefits of Phase 1 Oncology Trials, 1991 through 2002 Download | |
| Mar 3, 2020 | 1167 | Petitioner's Demonstratives Download | |
| Dec 12, 2019 | 1166 | Beumer et al., 156 Breast Cancer Res. Treatment 279 (2016) Download | |
| Dec 12, 2019 | 1165 | CAMPTOSAR Injection Label Download | |
| Dec 12, 2019 | 1164 | AVASTIN For Intravenous Use Label Download | |
| Dec 12, 2019 | 1163 | HERCEPTIN Label Download | |
| Dec 12, 2019 | 1162 | Paclitaxel Injection Label Download | |
| Dec 12, 2019 | 1161 | TAXOL Injection Label Download | |
| Dec 12, 2019 | 1160 | FEMARA Label Download | |
| Dec 12, 2019 | 1159 | GEMZAR Injection Label Download | |
| Dec 12, 2019 | 1158 | Fluorouracil Injection Label Download | |
| Dec 12, 2019 | 1157 | AROMASIN Label Download | |
| Dec 12, 2019 | 1156 | Doxorubicin Hydrochloride for Injection Label Download | |
| Dec 12, 2019 | 1155 | XEXLODA Label Download | |
| Dec 12, 2019 | 1154 | Approval Package for STILBESTROL Download | |
| Dec 12, 2019 | 1153 | National Women's Health Network Download | |
| Dec 12, 2019 | 1152 | Clinical Trial Ref. No. NCT01051596 Download | |
| Dec 12, 2019 | 1151 | Clinical Trial Ref. No. NCT00305838 Download | |
| Dec 12, 2019 | 1150 | Clinical Trial Ref. No. NCT00113373 Download | |
| Dec 12, 2019 | 1149 | Clinical Trial Ref. No. NCT00066339 Download | |
| Dec 12, 2019 | 1148 | Clinical Trial Ref. No. NCT00065533 Download | |
| Dec 12, 2019 | 1147 | Clinical Trial Ref. No. NCT00006121 Download | |
| Dec 12, 2019 | 1146 | Fluorouracil Injection Label Download | |
| Dec 12, 2019 | 1145 | Longley et al., 3 Nature Reviews Cancer 330 (2003) Download | |
| Dec 12, 2019 | 1144 | Etienne et al., 12 J. Clinical Oncology 2248 (1994) Download | |
| Dec 12, 2019 | 1143 | Kouwaki et al. 4 Clinical Cancer Res. 2999 (1998) Download | |
| Dec 12, 2019 | 1142 | U.S. Patent No. 8,700,335 Download | |
| Dec 12, 2019 | 1141 | File History Excerpt for U.S. Patent Application No. 11/750,721 Download | |
| Dec 12, 2019 | 1140 | U.S. Patent Application Publication No. 2008-0014146 Download | |
| Dec 12, 2019 | 1139 | U.S. Provisional Patent Application No. 60/747,645 Download | |
| Dec 12, 2019 | 1138 | NFCR profile for Dr. Brian Leyland-Jones Download | |
| Dec 12, 2019 | 1137 | LinkedIn profile for Dr. Jeffrey Settleman Download | |
| Dec 12, 2019 | 1136 | LinkedIn profile for Dr. Nadia Godin-Heymann Download | |
| Dec 12, 2019 | 1135 | LinkedIn profile for Dr. Eunice Kwak Download | |
| Dec 12, 2019 | 1134 | Cold Spring Harbor Laboratory profile for Dr. Raffaella Sordella Download | |
| Dec 12, 2019 | 1133 | NFCR profile for Dr. Daniel A. Haber Download | |
| Dec 12, 2019 | 1132 | LinkedIn profile for Dr. Eugene Chudin Download | |
| Dec 12, 2019 | 1131 | LinkedIn profile for Dr. Joanne Yeakley Download | |
| Dec 12, 2019 | 1130 | LinkedIn profile for Dr. Marina Bibikova Download | |
| Dec 12, 2019 | 1129 | LinkedIn profile for Dr. David Loesch Download | |
| Dec 12, 2019 | 1128 | LinkedIn profile for Dr. Alan Wright Download | |
| Dec 12, 2019 | 1127 | LinkedIn profile for Dr. Arlet Alarcon Download | |
| Dec 12, 2019 | 1126 | LinkedIn profile for Dr. Traci Pawlowski Download | |
| Dec 12, 2019 | 1125 | LinkedIn profile for Dr. Ryan Bender Download | |
| Dec 12, 2019 | 1124 | LinkedIn profile for Dr. Matthew McGinniss Download | |
| Dec 12, 2019 | 1123 | LinkedIn profile for Dr. Robert J. Penny Download | |
| Dec 12, 2019 | 1122 | HUGO Gene Nomenclature Committee Symbol Report Download | |
| Dec 12, 2019 | 1121 | Mori et al., 17 Intl J. Oncology 33 (2000) Download | |
| Dec 12, 2019 | 1120 | Reply Declaration of Paul T. Spellman, Ph.D. Download | |
| Dec 12, 2019 | 1119 | Deposition Transcript of Joyce A. O'Shaughnessy, M.D., Volume 2 of 2 Download | |
| Dec 12, 2019 | 1118 | Deposition Transcript of Joyce A. O'Shaughnessy, M.D., Volume 1 of 2 Download | |
| Dec 12, 2019 | 1117 | Chen, 9 The Oncologist 27 (2004) Download | |
| Sep 13, 2019 | 1116 | Ferrera Declaration Download | |
| Jul 3, 2019 | 1115 | Declaration Of Shirley X. Li Cantin In Support Of Motion For Admission Pro Hac Vice Download | |
| Jul 3, 2019 | 1114 | Declaration Of David B. Bassett In Support Of Motion For Admission Pro Hac Vice Download | |
| Jun 24, 2019 | 1113 | Natalie Stickle and Neil Winegarden, Toward the Realization of the Promise of Microarrays in Oncology, Genomics and Pharmacogenomics, in Anticancer Drug Development and Clinical Response (Federico Innocenti ed., 2008) Download | |
| Jun 24, 2019 | 1112 | A. Mitra et al., Melanoma Sentinel Node Biopsy and Prediction Models for Relapse and Overall Survival, 103 Brit. J. Cancer 1229 (2010) Download | |
| Jun 24, 2019 | 1111 | Marina Bibikova et al., Quantitative Expression Profiling of RNA from Formalin-Fixed, Paraffin-Embedded Tissues Using Randomly Download | |
| Jun 24, 2019 | 1110 | Andrew C. Haller et al., Transcriptional Profiling of Degraded RNA in Cryopreserved and Fixed Tissue Samples Obtained at Autopsy, 6:9 BMC Clinical Pathology (2006) Download | |
| Jun 24, 2019 | 1109 | Declaration of Sylvia Hall-Ellis (May 31, 2019) (Part 1) Download | |
| Jun 24, 2019 | 1109 | Declaration of Sylvia Hall-Ellis (May 31, 2019) (Part 1) Download | |
| Jun 24, 2019 | 1109 | Declaration of Sylvia Hall-Ellis (May 31, 2019) (Part 2 of 2) Download | |
| Jul 29, 2019 | 1109 | Declaration of Sylvia Hall-Ellis, Ph.D. Download | |
| Jun 24, 2019 | 1108 | Affymetrix, Inc. v. Illumina, Inc., No. 1:04-cv-00901-JJF, D.I. 357 (D. Del. Feb. 5, 2007) Download | |
| Jun 24, 2019 | 1107 | Affymetrix, Inc. v. Illumina, Inc., No. 1:04-cv-00901-JJF, D.I. 209 (D. Del. Feb. 9, 2006) Download | |
| Jun 24, 2019 | 1106 | Affymetrix, Inc. v. Illumina, Inc., No. 1:04-cv-00901-JJF, D.I. 140 (D. Del. Dec. 22, 2005) Download | |
| Jun 24, 2019 | 1105 | Declaration of George Yu (June 3, 2019) Download | |
| Jun 24, 2019 | 1104 | Illumina Seminar Series Notice, University of Florida, From Whole- Genome to Whole-Solution, Disease Analysis Tools for the Next Generation (Feb. 15, 2007) Download | |
| Jun 24, 2019 | 1103 | Seminar Notice, Sunnybrook Research Institute, Applying Genomic and Proteomic Platforms Towards the Individualization of Treatment for Breast Cancer Patients (Oct. 25, 2006) Download | |
| Jun 24, 2019 | 1102 | Fixed on Expression, 4 Bio-IT World 22 (2005) Download | |
| Jun 24, 2019 | 1101 | Jian-Bing Fan et al., Multiplexed RNA Profiling of Paraffin Samples - Assay Tutorial Reproducible Gene Expression from Degraded RNAs Using the DASL Download | |
| Jun 24, 2019 | 1101 | Download | |
| Jun 24, 2019 | 1100 | Mark Abramovitz & Brian Leyland-Jones, A Systems Approach to Clinical Oncology: Focus on Breast Cancer, 4 Proteome Sci. (2006) Download | |
| Jun 24, 2019 | 1099 | Declaration of Mark Abramovitz (June 3, 2019) Download | |
| Jul 15, 2019 | 1098 | Corrected Affidavit of Christopher Butler Download | |
| Jun 24, 2019 | 1098 | Affidavit of Christopher Butler (May 10, 2019) Download | |
| Nov 5, 2018 | 1065 | Complaint Download | |
| Nov 5, 2018 | 1064 | Federico Cappuzzo et al., Clinical experience with gefitinib: An update, 58 Critical Reviews in Oncology/Hematology 31 (2006) Download | |
| Nov 5, 2018 | 1063 | Dan L. Longo, Imatinib Changed Everything, 376 New England J. Med. 982 (2017) Download | |
| Nov 5, 2018 | 1062 | Claudia Dreifus, Researcher Behind the Drug Gleevec, N.Y. Times (Nov. 2, 2009), at D4 Download | |
| Nov 5, 2018 | 1061 | NIH National Cancer Institute, How Imatinib Transformed Leukemia Treatment and Cancer Research, (updated Apr. 11, 2018) https://www.cancer.gov/research/progress/discovery/gleevec Download | |
| Nov 5, 2018 | 1060 | HUGO Gene Nomenclature Committee Symbol Report: ESR1, available at https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:3467 Download | |
| Nov 5, 2018 | 1059 | Phillip G. Febbo & Geoffrey S. Ginsburg, Personalized diagnostic and therapeutic strategies in oncology, 2 Personalized Medicine 97 (2005) Download | |
| Nov 5, 2018 | 1058 | HUGO Gene Nomenclature Committee Symbol Report: CASP8, available at https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:1509 Download | |
| Nov 5, 2018 | 1057 | G. William Moore et al., A Prototype Internet Autopsy Database: 1625 Consecutive Fetal and Neonatal Autopsy Facesheets Spanning Twenty Years, 120 Archives Pathology Lab. Med. 782 (1996) Download | |
| Nov 5, 2018 | 1056 | Timothy K. Egan, Monitoring Patients Undergoing Cancer Therapy, 31 Lab. Med. 666 (2000) Download | |
| Nov 5, 2018 | 1055 | David S. Wishart et al, DrugBank: a comprehensive resource for in silico drug discovery and exploration, 34 Nucleic Acids Research D668 (2006) Download | |
| Nov 5, 2018 | 1054 | U.S. Patent No. 9,092,392 (the " '392 patent") Download | |
| Nov 5, 2018 | 1053 | Jian-Bing Fan et al., BeadArrayTM-based solutions for enabling the promise of pharmacogenomics, 39 BioTechniques 583 (2005) Download | |
| Nov 5, 2018 | 1052 | David Stipp, Gene Chip Breakthrough, Fortune Magazine, Mar. 31, 1997, at 56 Download | |
| Nov 5, 2018 | 1051 | Masuko Katoh & Masaru Katoh, Bioinformatics for Cancer Management in the Post-Genome Era, 5 Technology in Cancer Research & Treatment 169 (2006) Download | |
| Nov 5, 2018 | 1050 | Jeffrey S. Ross & Geoffrey S. Ginsburg, The Integration of Molecular Diagnostics with Therapeutics: Implications for Drug Development and Pathology Practice, 119 Am. J. Clinical Pathology 26 (2003) ("Ross") Download | |
| Nov 5, 2018 | 1049 | Jian-Bing Fan et al., A Versatile Assay for High-Throughput Gene Expression Profiling on Universal Array Matrices, 14 Genome Research 878 (2004) Download | |
| Nov 5, 2018 | 1048 | Marina Bibikova et al., Quantitative Gene Expression Profiling in Formalin-Fixed, Paraffin-Embedded Tissues Using Universal Bead Arrays, 165 American J. Pathology 1799 (2004) Download | |
| Nov 5, 2018 | 1047 | Marina Bibikova et al., Gene Expression Profiles in Formalin-Fixed, Paraffin-Embedded Tissues Obtained with a Novel Assay for Microarray Analysis, 50 Clinical Chemistry 2384 (2004) Download | |
| Nov 5, 2018 | 1046 | Business Wire, Illumina Launches DASL Assay and Cancer Panel for Gene Expression Profiling of Paraffin-Embedded Samples (Jan. 13, 2005) Download | |
| Nov 5, 2018 | 1045 | HUGO Gene Nomenclature Committee Symbol Report: ERBB2, available at https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:3430 Download | |
| Nov 5, 2018 | 1044 | HUGO Gene Nomenclature Committee Symbol Report: EGFR, available at https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:3236 Download | |
| Nov 5, 2018 | 1043 | Xiaojun Zhao et al., Homozygous Deletions and Chromosome Amplifications in Human Lung Carcinomas Revealed by Single Nucleotide Polymorphism Array Analysis, 65 Cancer Research 5561 (2005) Download | |
| Nov 5, 2018 | 1042 | Oxford Dictionary of Biochemistry and Molecular Biology (Oxford University Press, 2d ed. 2006) Download | |
| Nov 5, 2018 | 1041 | U.S. Provisional Patent Application No. 60/747,645 Download | |
| Nov 5, 2018 | 1040 | Timothy R. Hughes et al., Functional Discovery via a Compendium of Expression Profiles, 102 Cell 109 (2000) Download | |
| Nov 5, 2018 | 1039 | Justin Lamb et al., The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease, 313 Science 1929 (2006) Download | |
| Nov 5, 2018 | 1038 | S. Forbes et al., COSMIC 2005, 94 British J. Cancer 318 (2006) Download | |
| Nov 5, 2018 | 1037 | X. Chen et al., TTD: Therapeutic Target Database, 30 Nucleic Acids Research 412 (2002) Download | |
| Nov 5, 2018 | 1036 | C.J. Zheng et al., TRMP: a database of therapeutically relevant multiple pathways, 20 Bioinformatics 2236 (2004) Download | |
| Nov 5, 2018 | 1035 | Alexander Statnikov et al., GEMS: A System for Automated Cancer Diagnosis and Biomarker Discovery from Microarray Gene Expression Data, 74 Int'l J. Med. Informatics 491 (2005) Download | |
| Nov 5, 2018 | 1034 | Jeremy Gollub et al., The Stanford Microarray Database: data access and quality assessment tools, 31 Nucleic Acids Research 94 (2003) Download | |
| Nov 5, 2018 | 1033 | H. Parkinson, ArrayExpress - a public repository for microarray gene expression data at the EBI, 33 Nucleic Acids Research D553 (2005) Download | |
| Nov 5, 2018 | 1032 | Daniel R. Rhodes et al., Oncomine 3.0: Genes, Pathways, and Networks in a Collection of 18,000 Cancer Gene Expression Profiles, 9 Neoplasia 166 (2007) Download | |
| Nov 5, 2018 | 1031 | Daniel R. Rhodes et al., Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression, 25 PNAS 9309 (2004) Download | |
| Nov 5, 2018 | 1030 | Daniel R. Rhodes et al., Oncomine: A Cancer Microarray Database and Integrated Data-Mining Platform, 6 Neoplasia 1, 1 (2004) Download | |
| Nov 5, 2018 | 1029 | Thomas Jarvie, Next generation sequencing technologies, 2 Drug Discovery Today: Technologies 255 (2005) Download | |
| Nov 5, 2018 | 1028 | Thomas M. Daly et al., Precision Profiling and Components of Variability Analysis for Affymetrix Microarray Assays Run in a Clinical Context, 7 J. Molecular Diagnostics 404 (2005) Download | |
| Nov 5, 2018 | 1027 | Atul J. Butte et al., Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks, 97 PNAS 12182 (2000) Download | |
| Nov 5, 2018 | 1026 | Jane E. Staunton et al., Chemosensitivity prediction by transcriptional profiling, 98 PNAS 10787 (2001) Download | |
| Nov 5, 2018 | 1025 | ErbituxTM (cetuximab) Prescribing Information (Mar. 1, 2006) Download | |
| Nov 5, 2018 | 1024 | Butler Affidavit Download | |
| Nov 5, 2018 | 1023 | ErbituxTM (cetuximab) Prescribing Information (Feb. 12, 2004) Download | |
| Nov 5, 2018 | 1022 | Henry Q. Xiong & James L. Abbruzzese, Epidermal growth factor receptor-targeted therapy for pancreatic cancer, 29 Seminars in Oncology 31 (2002) Download | |
| Nov 5, 2018 | 1021 | NCI Drug Dictionary, https://www.cancer.gov/publications/dictionaries/cancer-drug/def/cetuximab Download | |
| Nov 5, 2018 | 1020 | ClinicalTrials.gov, Study of TARCEVA (Erlotinib) as Adjuvant Treatment for Locally Advanced Head and Neck Squamous Cell Carcinoma, available at https://clinicaltrials.gov/ct2/show/NCT01515137 Download | |
| Nov 5, 2018 | 1019 | James Moyer et al., Induction of Apoptosis and Cell Cycle Arrest by CP-358,774, an Inhibitor of Epidermal Growth Factor Receptor Tyrosine Kinase, 57 Cancer Research 4838 (1997) Download | |
| Nov 5, 2018 | 1018 | TarcevaTM (erlotinib) Prescribing Information (Nov. 18, 2004) Download | |
| Nov 5, 2018 | 1017 | IressaTM (gefitinib) Prescribing Information (May 2, 2003) Download | |
| Nov 5, 2018 | 1016 | S. Scholl, Targeting HER2 in Other Tumor Types, 12 Annals Oncology S81 (2001) Download | |
| Nov 5, 2018 | 1015 | Herceptin® (trastuzumab) Prescribing Information (Sept. 1998) Download | |
| Nov 5, 2018 | 1014 | GleevecTM (imatinib mesylate) Prescribing Information (Jan. 22, 2002) Download | |
| Nov 5, 2018 | 1013 | Nida Iqbal & Naveed Iqbal, Imatinib: A Breakthrough of Targeted Therapy in Cancer, Chemotherapy Research & Practice 1 (2014) Download | |
| Nov 5, 2018 | 1012 | Jackson B. Gibbs, Anticancer drug targets: growth factors and growth factor signaling, 105 J. Clinical Investigation 9 (2000) Download | |
| Nov 5, 2018 | 1011 | Genomics and Personalized Medicine Act of 2006, S. 3822, 109th Cong Download | |
| Nov 5, 2018 | 1010 | NHGRI Seeks Next Generation of Sequencing Technologies (Oct. 14, 2004) Download | |
| Nov 5, 2018 | 1009 | Charles Sawyers, Targeted cancer therapy, 432 Nature 294, (2004) Download | |
| Nov 5, 2018 | 1008 | Robert Langreth & Michael Waldholz, New Era of Personalized Medicine Targeting Drugs For Each Unique Genetic Profile, 4 The Oncologist 426 (1999) Download | |
| Nov 5, 2018 | 1007 | Amy L. McDoniels-Silvers et al., Differential Expression of Critical Cellular Genes in Human Lung Adenocarcinomas and Squamous Cell Carcinomas in Comparison to Normal Lung Tissues, 4 Neoplasia 141 (2002) Download | |
| Nov 5, 2018 | 1006 | U.S. Patent Publication No. 2002/0150966 ("Muraca") Download | |
| Nov 5, 2018 | 1005 | Illumina R Gene Expression Profiling, Technical Bulletin, RNA Profiling with the DASL R Assay (2005) ("Illumina") Download | |
| Nov 5, 2018 | 1004 | PCT Publication No. WO 03/017038 (published Feb. 27, 2003) ("Lu") Download | |
| Nov 5, 2018 | 1003 | File History Excerpt Download | |
| Nov 5, 2018 | 1002 | Declaration of Paul T. Spellman, Ph.D. Download | |
| Nov 5, 2018 | 1001 | U.S. Patent No.9,372,193 (the"'193 patent") Download | |
| Jun 2, 2020 | 57 | Patent Owner's Notice of Appeal Download | |
| May 28, 2020 | 56 | Judgment - Final Written Decision - Determining All Challenged Claims Unpatentable Download | |
| Mar 27, 2020 | 55 | Petitioner's Updated Mandatory Notices Download | |
| Mar 18, 2020 | 54 | Hearing Transcript Download | |
| Mar 3, 2020 | 53 | Petitioner's Updated Exhibit List Download | |
| Mar 3, 2020 | 52 | Patent Owner's Updated Exhibit List Download | |
| Jan 27, 2020 | 51 | ORDER Oral Hearing 37 C.F.R. 42.70 Download | |
| Jan 23, 2020 | 50 | Patent Owner's Sur-Reply Download | |
| Jan 21, 2020 | 49 | PETITIONER'S REQUEST FOR ORAL ARGUMENT Download | |
| Jan 21, 2020 | 48 | Patent Owner's Request for Oral Argument Download | |
| Jan 14, 2020 | 47 | Patent Owner's Updated Mandatory Notices Download | |
| Jan 10, 2020 | 46 | Order - Modifying the Scheduling Order - 37 CFR 42.5(c) Download | |
| Jan 10, 2020 | 45 | Decision - Granting Patent Owner's Motions for Pro Hac Vice Admission of Jonathan Singer - 37 CFR 42.10 Download | |
| Dec 30, 2019 | 44 | Patent Owner's Notice of Deposition of Paul T. Spellman, Ph.D Download | |
| Dec 12, 2019 | 43 | PETITIONER'S REPLY TO PATENT OWNER'S RESPONSE Download | |
| Dec 5, 2019 | 42 | Patent Owner's Unopposed Motion for Pro Hac Vice Admission of Jonathan Singer Download | |
| Nov 21, 2019 | 41 | Download | |
| Oct 18, 2019 | 40 | Patent Owner's Updated Power of Attorney Download | |
| Oct 18, 2019 | 39 | Patent Owner's Updated Mandatory Notices Download | |
| Oct 15, 2019 | 38 | Granting Patent Owner's Motions for Pro Hac Vice Admission of Christina Brown-Marshall Download | |
| Oct 15, 2019 | 37 | Granting Patent Owner's Motions for Pro Hac Vice Admission of Corrin Drakulich Download | |
| Oct 4, 2019 | 36 | Patent Owner's Unopposed Motion for Pro Hac Vice Admission of Corrin Drakulich Download | |
| Oct 3, 2019 | 35 | Patent Owner's Unopposed Motion for Pro Hac Vice Admission of Christina Brown-Marshall Download | |
| Sep 27, 2019 | 34 | Petitioner's Notice of Deposition of Joyce A. O'Shaughnessy, M.D. Download | |
| Sep 19, 2019 | 33 | Patent Owner's Response Download | |
| Sep 19, 2019 | 32 | Hanahan, et al., ¿¿¿The Hallmarks of Cancer,¿¿¿ Cell, Vol. 100, 57-70, January 7, 2000 Download | |
| Sep 18, 2019 | 31 | Decision Granting Petitioner's Motions for Pro Hac Vice Admission of Vinita Ferrera Download | |
| Sep 18, 2019 | 30 | Petitioner's Updated Mandatory Notices Download | |
| Sep 13, 2019 | 29 | Petitioner's Motion For Admission Pro Hac Vice of Vinita Ferrera Download | |
| Aug 6, 2019 | 28 | Patent Owner's Cancellation of Deposition Download | |
| Jul 30, 2019 | 27 | Patent Owner's Notice of Deposition of Mark Abramovitz, Ph.D Download | |
| Jul 29, 2019 | 26 | Joint Stipulation to Modify Due Dates 1-3 Download | |
| Jul 23, 2019 | 25 | Decision Granting Petitioner's Motions for Pro Hac Vice Admission of Shirley X. Li Cantin Download | |
| Jul 23, 2019 | 24 | Decision Granting Petitioner's Motions for Pro Hac Vice Admission of David B. Bassett Download | |
| Jul 22, 2019 | 23 | Granting Petitioner's Motion to File Supplemental Information Download | |
| Jul 19, 2019 | 22 | Petitioner's Updated Mandatory Notices Download | |
| Jul 15, 2019 | 21 | ORDER Conduct of the Proceeding Download | |
| Jul 3, 2019 | 20 | Petitioners Motion For Admission Pro Hac Vice Of Shirley X. Li Cantin Download | |
| Jul 3, 2019 | 19 | Petitioners Motion For Admission Pro Hac Vice Of David B. Bassett Download | |
| Jul 1, 2019 | 18 | Patent Owner's Opposition to Petitioner's Motion to Submit Supplemental Information Download | |
| Jun 24, 2019 | 17 | PETITIONER'S MOTION TO SUBMIT SUPPLEMENTAL INFORMATION Download | |
| Jun 18, 2019 | 16 | Order - Conduct of the Proceedings - 37 CFR 42.5 Download | |
| Jun 17, 2019 | 15 | Notice of Deposition of Paul T. Spellman, Ph.D Download | |
| Jun 13, 2019 | 14 | Patent Owner's Objections to Evidence Download | |
| May 30, 2019 | 13 | Scheduling Order Download | |
| May 30, 2019 | 12 | Trial Instituted Document Download | |
| Apr 22, 2019 | 11 | PANEL CHANGE ORDER Conduct of the Proceedings 37 C.F.R. ¿¿ 42.5 Download | |
| Mar 29, 2019 | 10 | Patent Owner's Sur-Reply Download | |
| Mar 22, 2019 | 9 | Petitioner's Reply to Patent Owner's Preliminary Response Download | |
| Mar 15, 2019 | 8 | Conduct of the Proceeding 37 C.F.R. sec. 42.5 Download | |
| Mar 6, 2019 | 7 | Patent Owner's Preliminary Response Download | |
| Dec 6, 2018 | 6 | Notice of Accord Filing Date Download | |
| Nov 19, 2018 | 5 | Patent Owner's Power of Attorney Download | |
| Nov 19, 2018 | 4 | Patent Owner's Mandatory Notices Download | |
| Nov 5, 2018 | 3 | Petition IPR2019-00170 Download | |
| Nov 5, 2018 | 2 | Fee Authorization Download | |
| Nov 5, 2018 | 1 | Power of Attorney Download |
