Case number IPR2019-00166
Foundation Medicine, Inc. v. Caris MPI, Inc. > Documents
| Date Field | Doc. No. | Party | Description |
|---|---|---|---|
| Jan 5, 2022 | 1143 | petitioner | Declaration of Jonathan Swisher in Support of Petitioner's Motion for Admission Pro Hac Vice Download |
| Jan 5, 2022 | 61 | petitioner | Petitioner's Motion for Admission Pro Hac Vice of Jonathan Swisher Download |
| Jan 5, 2022 | 62 | petitioner | Petitioner's Updated Exhibit List Download |
| Jan 3, 2022 | 60 | board | Order: Other Download |
| Dec 16, 2021 | 57 | petitioner | PETITIONER'S MOTION FOR WITHDRAWAL OF COUNSEL Download |
| Dec 16, 2021 | 58 | petitioner | PETITIONER'S UPDATED MANDATORY NOTICES Download |
| Dec 16, 2021 | 59 | petitioner | PETITIONER'S POWER OF ATTORNEY Download |
| Jun 16, 2020 | 56 | Petitioner's Notice of Cross-Appeal Download | |
| Jun 2, 2020 | 54 | Patent Owner's Notice of Appeal Download | |
| May 13, 2020 | 53 | Termination Decision Document Download | |
| May 11, 2020 | 52 | Hearing Transcript Download | |
| Mar 27, 2020 | 50 | Petitioner's Updated Mandatory Notices Download | |
| Feb 10, 2020 | 49 | Petitioner's Updated Mandatory Notices And Exhibit List Download | |
| Jan 23, 2020 | 48 | Download | |
| Jan 14, 2020 | 47 | Patent Owner's Updated Mandatory Notices Download | |
| Jan 10, 2020 | 46 | Decision - Granting Patent Owner's Motions for Pro Hac Vice Admission of Jonathan Singer - 37 CFR 42.10 Download | |
| Jan 3, 2020 | 45 | Patent Owner's Sur-Reply Download | |
| Dec 30, 2019 | 43 | Petitioner's Request for Oral Argument Download | |
| Dec 30, 2019 | 44 | Patent Owner's Request for Oral Argument Download | |
| Dec 5, 2019 | 2056 | Declaration of Jonathan Singer Download | |
| Dec 5, 2019 | 42 | Patent Owner's Unopposed Motion for Pro Hac Vice Admission of Jonathan Singer Download | |
| Nov 22, 2019 | 1117 | Chen Download | |
| Nov 22, 2019 | 1118 | O'Shaughnessy Deposition Transcript Volume 1 10-22-19 Download | |
| Nov 22, 2019 | 1119 | O'Shaughnessy Deposition Transcript Volume 2 10-23-19 Download | |
| Nov 22, 2019 | 1120 | Reply Declaration of Paul T. Spellman, Ph.D. Download | |
| Nov 22, 2019 | 1121 | U.S. Pat. No. 9,053,224 Download | |
| Nov 22, 2019 | 1122 | File History Excerpt for U.S. Pat. App. No. 12/658,770 Download | |
| Nov 22, 2019 | 1123 | Penny LinkedIn Profile Download | |
| Nov 22, 2019 | 1124 | McGinniss LinkedIn Profile Download | |
| Nov 22, 2019 | 1125 | Bender LinkedIn Profile Download | |
| Nov 22, 2019 | 1126 | Pawlowski LinkedIn Profile Download | |
| Nov 22, 2019 | 1127 | Alarcon LinkedIn Profile Download | |
| Nov 22, 2019 | 1128 | Wright LinkedIn Profile Download | |
| Nov 22, 2019 | 1129 | Loesch LinkedIn Profile Download | |
| Nov 22, 2019 | 1130 | Bibikova LinkedIn Profile Download | |
| Nov 22, 2019 | 1131 | Yeakley LinkedIn Profile Download | |
| Nov 22, 2019 | 1132 | Chudin LinkedIn Profile Download | |
| Nov 22, 2019 | 1133 | Haber NFCR Profile Download | |
| Nov 22, 2019 | 1134 | Sordella Cold Spring Harbor Laboratory Profile Download | |
| Nov 22, 2019 | 1135 | Kwak LinkedIn Profile Download | |
| Nov 22, 2019 | 1136 | Godin-Heymann LinkedIn Profile Download | |
| Nov 22, 2019 | 1137 | Settleman LinkedIn Profile Download | |
| Nov 22, 2019 | 1138 | Leyland-Jones NFCR Profile Download | |
| Nov 22, 2019 | 1139 | Puzanov Download | |
| Nov 22, 2019 | 1140 | Gustin Download | |
| Nov 22, 2019 | 1141 | Mittendorf Download | |
| Nov 22, 2019 | 1142 | Riely Download | |
| Nov 22, 2019 | 41 | Petitioner's Reply to Patent Owner's Response Download | |
| Nov 21, 2019 | 40 | Download | |
| Oct 18, 2019 | 38 | Patent Owner's Updated Mandatory Notices Download | |
| Oct 18, 2019 | 39 | Patent Owner's Updated Power of Attorney Download | |
| Oct 15, 2019 | 36 | Granting Patent Owner's Motions for Pro Hac Vice Admission of Corrin Drakulich Download | |
| Oct 15, 2019 | 37 | Granting Patent Owner's Motions for Pro Hac Vice Admission of Christina Brown-Marshall Download | |
| Oct 4, 2019 | 2055 | Declaration of Corrin Drakulich Download | |
| Oct 4, 2019 | 35 | Patent Owner's Unopposed Motion for Pro Hac Vice Admission of Corrin Drakulich Download | |
| Oct 3, 2019 | 2054 | Declaration of Christina Brown-Marshall Download | |
| Oct 3, 2019 | 34 | Patent Owner's Unopposed Motion for Pro Hac Vice Admission of Christina Brown-Marshall Download | |
| Sep 27, 2019 | 33 | Petitioner's Notice of Deposition of Joyce A. O'Shaughnessy, M.D. Download | |
| Sep 18, 2019 | 32 | Decision Granting Petitioner's Motions for Pro Hac Vice Admission of Vinita Ferrera Download | |
| Sep 18, 2019 | 31 | Petitioner's Updated Mandatory Notices Download | |
| Sep 13, 2019 | 30 | Petitioner's Motion For Admission Pro Hac Vice of Vinita Ferrera Download | |
| Sep 13, 2019 | 1116 | Ferrera Declaration Download | |
| Aug 30, 2019 | 2053 | FoundationOne¿¿CDX Webpage, downloaded from the internet at https://www.foundationmedicine.com/genomic-testing/foundationone-cdx#overview on August 28, 2019, 12 pages Download | |
| Aug 30, 2019 | 29 | Patent Owner's Response Download | |
| Aug 30, 2019 | 2022 | National Comprehensive Cancer Network, "Breast Cancer Clinical Practice Guidelines in Oncology", Journal of the National Comprehensive Cancer Network, Vol. 7, No. 2, February 2009, pp. 122-192 Download | |
| Aug 30, 2019 | 2023 | Part 1 of 2 - National Comprehensive Cancer Network, "Non-Small Cell Lung Cancer Clinical Practice Guidelines in Oncology", Journal of the National Comprehensive Cancer Network, Vol. 4, No. 6, July 2006, pp. 547-582 Download | |
| Aug 30, 2019 | 2047 | Haber et al., "Molecular Targeted Therapy of Lung Cancer: EGFR Mutations and Response to EGFR Inhibitors," Cold Spring Harbor Laboratory Press, Vol. LXX, 2005, pp. 419-426 Download | |
| Aug 30, 2019 | 2035 | Foundation Medicine, Inc., Form 10-K, filed March 3, 2017 for the period ending December 31, 2016 Download | |
| Aug 30, 2019 | 2048 | F Loupakis et. al, "KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer," British Journal of Cancer, Vol. 101, No. 4, July 14, 2009, pp. 715-721 Download | |
| Aug 30, 2019 | 2021 | National Comprehensive Cancer Network, "Gastric Cancer Clinical Practice Guidelines in Oncology", Journal of the National Comprehensive Cancer Network, Vol. 1, No. 1, January 2003, pp. 27-39 Download | |
| Aug 30, 2019 | 2052 | FoundationOne¿¿HEME Technical Specification, downloaded from the internet at https://assets.ctfassets.net/vhribv12lmne/zBxaQC12cScqgsEk8seMO/c32a7d1adf083cb0f5d0c0b2439fdb87/F1H_Technical_Information.pdf on August 28, 2019, 3 pages Download | |
| Aug 30, 2019 | 2045 | Azzoli et. al, "American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non-Small Cell Lung Cancer," ASCO, January 2010, pp. 39-43 Download | |
| Aug 30, 2019 | 2051 | FoundationOne¿¿Liquid Technical Specification, downloaded from the internet at https://assets.ctfassets.net/vhribv12lmne/3SPYAcbGdqAeMsOqMyKUog/d0eb51659e08d733bf39971e85ed940d/F1L_TechnicalInformation_MKT-0061-04.pdf on August 28, 2019, 2 pages Download | |
| Aug 30, 2019 | 2024 | National Comprehensive Cancer Network, "Breast Cancer Version 4.2017 Clinical Practice Guidelines in Oncology", Journal of the National Comprehensive Cancer Network, Vol. 16, No. 3, March 2018, pp. 310-320 Download | |
| Aug 30, 2019 | 2039 | Paez et al., "EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy," Science, Vol. 304, June 4, 2004, pp. 1497-1500 Download | |
| Aug 30, 2019 | 2042 | Tanner et. al, "Amplification of HER-2 in Gastric Carcinoma," Annals of Oncology, Vol. 16, 2005, pp. 273-278 Download | |
| Aug 30, 2019 | 2030 | Gleevec¿¿ FDA 2002 Approval Letter downloaded from https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=021335 on August 19, 2019, 4 pages Download | |
| Aug 30, 2019 | 2037 | Shen et al., "Utilization Patterns and Trends in Epidermal Growth Factor Receptor (EGFR) Mutation Testing among Patients with Newly Diagnosed Metastatic Lung Cancer," Clinical Lung Cancer, Vol. 18, No. 4, July 2017, pp. e233-e241 Download | |
| Aug 30, 2019 | 2016 | Expert Declaration of Joyce O¿¿¿Shaughnessy, M.D. Download | |
| Aug 30, 2019 | 2033 | Von Hoff et al., "Frequency of Potential Therapeutic Targets Identified by IHC and DNA Microarray in Tumors From Patients Who Have Progressed on Multiple Therapeutic Agents," Journal of Clinical Oncology, Vol. 24, No. 18. Suppl.3 Download | |
| Aug 30, 2019 | 2023 | Part 1 of 2 - National Comprehensive Cancer Network, "Non-Small Cell Lung Cancer Clinical Practice Guidelines in Oncology", Journal of the National Comprehensive Cancer Network, Vol. 4, No. 6, July 2006, pp. 547-582 Download | |
| Aug 30, 2019 | 2019 | Hanahan, et al., "The Hallmarks of Cancer," Cell, Vol. 100, 57-70, January 7, 2000 Download | |
| Aug 30, 2019 | 2038 | Lynch et al., "Activating mutation in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib," NEJM, Vol. 350, May 20, 2004, Abstract Download | |
| Aug 30, 2019 | 2043 | Flavell, "Keytruda," Immuno-Oncology News, downloaded from the internet at https://immuno-oncologynews.com/keytrudapembrolizumab/ on August 15, 2019, 8 pages Download | |
| Aug 30, 2019 | 2032 | Richard Simon, "Roadmap for Developing and Validating Therapeutically Relevant Genomic Classifiers," Journal of Clinical Oncology, Vol. 23, No. 29, October 10, 2005, pp. 7332-7341 Download | |
| Aug 30, 2019 | 2015 | Deposition Transcript of Paul Spellman, Ph.D., Foundation Medicine V. Caris MPI, Inc. July 25, 2019 Download | |
| Aug 30, 2019 | 2018 | Foundation Medicine, Inc., "Foundation One: Technical Information and Test Overview", downloaded from the internet at www.foundationone.com on March 4, 2019, 2 pages Download | |
| Aug 30, 2019 | 2031 | Avastin¿¿, Highlights of Prescribing Information downloaded from the internet at https://www.gene.com/download/pdf/avastin_prescribing.pdf on August 15, 2019, 39 pages Download | |
| Aug 30, 2019 | 2027 | National Comprehensive Cancer Network, "Colon Cancer Version 1.2017 Clinical Practice Guidelines in Oncology", Journal of the National Comprehensive Cancer Network, Vol. 15, No. 3, March 2017, pp. 370-398 Download | |
| Aug 30, 2019 | 2049 | Sartore-Bianch et al., "PIK3CA Mutations in Colorectal Cancer Associated with Clinical Resistance to EGFR-Targeted Monoclonal Antibodies," Cancer Research, Vol. 69, No. 5, March 1, 2009, pp. 1851-1857 Download | |
| Aug 30, 2019 | 2036 | Gleevec¿¿ Label, downloaded from https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=021335 on August 19, 2019, 22 pages Download | |
| Aug 30, 2019 | 2028 | Gleevec¿¿ FDA 2001 Approval Letter downloaded from https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=021335 on August 19, 2019, 3 pages Download | |
| Aug 30, 2019 | 2044 | Yang, "Epidemiology of Lung Cancer Prognosis: Quantity and Quality of Life," Methods Mol Biol., September 17, 2010, Vol. 471, pp. 1-17 Download | |
| Aug 30, 2019 | 2026 | Corless et al., "Tackling Formalin-Fixed, Paraffin-Embedded Tumor Tissue with Next-Generation Sequencing," Cancer Discovery, January 12, 2012, pp. 23-24 Download | |
| Aug 30, 2019 | 2020 | Sorlie, et al., ¿¿¿Repeated Observation of Breast Tumor Subtypes in Independent Gene Expression Sets,¿¿¿ PNAS Vol. 100, No. 14, July 8, 2003, pp. 8418-8423. Download | |
| Aug 30, 2019 | 2046 | Fuest, "Dan Von Hoff¿¿¿s Karnofsky Lecture: Smart Phase I Trials Can Extend Life Beyond ¿¿¿The Last 12 Weeks,'" Oncology Times ASCO Meeting Reporter Supplement, August 10, 2010, pp. 21-23 Download | |
| Aug 30, 2019 | 2034 | National Comprehensive Cancer Network, "Small Cell Lung Cancer Clinical Practice Guidelines in Oncology", Journal of the National Comprehensive Cancer Network, Vol. 4, No. 6, July 2006, pp. 601-622 Download | |
| Aug 30, 2019 | 2025 | The Cancer Genome Atlas Research Network et al., "The Cancer Genome Atlas Pan-Cancer Analysis Project," Nature Genetics, Vol. 45, No. 10, October 2013, pp. 1113-1120 Download | |
| Aug 30, 2019 | 2050 | Black et al., "Sensitivity to Epidermal Growth Factor Receptor Inhibitor Requires E-Cadherin Expression in Urothelial Carcinoma Cells", Clinical Cancer Research, Vol. 14, No. 5, March 1, 2008, pp.1478-1486 Download | |
| Aug 30, 2019 | 2029 | Leslie A. Pray, "Gleevec¿¿: The Breakthrough in Cancer Treatment," Nature Education, Vol. 1, 2008, 4 pages Download | |
| Aug 30, 2019 | 2041 | Kari et. al, "Targeting the Epidermal Growth Factor in Cancer," Cancer Research, Vol. 63, January 1, 2003, pp. 1-5 Download | |
| Aug 30, 2019 | 2017 | "Dr. Daniel Von Hoff Presented With Top Genomics Award from Scripps" downloaded from the internet at https://www.eurekalert.org/pub_releases/2011-03/ttgrddv031711.php on August 30, 2019 Download | |
| Aug 30, 2019 | 2040 | Pao et al., "EGF receptor gene mutations are common in lung cancers from ¿¿¿never smokers¿¿¿ and correlate with sensitivity of tumors to gefitinib (Iressa) and erlotinib (Tarceva)," PNAS, Vol. 101, No. 36, September 7, 2004, pp. 13306-13311 Download | |
| Aug 30, 2019 | 2023 | Part 2 of 2 - National Comprehensive Cancer Network, "Non-Small Cell Lung Cancer Clinical Practice Guidelines in Oncology", Journal of the National Comprehensive Cancer Network, Vol. 4, No. 6, July 2006, pp. 547-582 Download | |
| Aug 6, 2019 | 28 | Patent Owner's Cancellation of Deposition Download | |
| Jul 30, 2019 | 27 | Patent Owner's Notice of Deposition of Mark Abramovitz, Ph.D Download | |
| Jul 29, 2019 | 1109 | Declaration of Sylvia Hall-Ellis, Ph.D. Download | |
| Jul 29, 2019 | 1109 | Declaration of Sylvia Hall-Ellis, Ph.D. Download | |
| Jul 29, 2019 | 26 | Joint Stipulation to Modify Due Dates 1-3 Download | |
| Jul 23, 2019 | 24 | Decision Granting Petitioner's Motions for Pro Hac Vice Admission of Shirley X. Li Cantin Download | |
| Jul 23, 2019 | 25 | Decision Granting Petitioner's Motions for Pro Hac Vice Admission of David B. Bassett Download | |
| Jul 22, 2019 | 23 | Granting Petitioner's Motion to File Supplemental Information Download | |
| Jul 22, 2019 | 3003 | Exhibit 3003 Download | |
| Jul 19, 2019 | 22 | Petitioner's Updated Mandatory Notices Download | |
| Jul 15, 2019 | 1098 | Corrected Affidavit of Christopher Butler Download | |
| Jul 15, 2019 | 21 | ORDER Conduct of the Proceeding Download | |
| Jul 15, 2019 | 3002 | Exhibit 3002 Download | |
| Jul 3, 2019 | 20 | Petitioners Motion For Admission Pro Hac Vice Of David B. Bassett Download | |
| Jul 3, 2019 | 1115 | Declaration Of Shirley X. Li Cantin In Support Of Motion For Admission Pro Hac Vice Download | |
| Jul 3, 2019 | 1114 | Declaration Of David B. Bassett In Support Of Motion For Admission Pro Hac Vice Download | |
| Jul 3, 2019 | 19 | Petitioners Motion For Admission Pro Hac Vice Of Shirley X. Li Cantin Download | |
| Jul 1, 2019 | 18 | Patent Owner's Opposition to Petitioner's Motion to Submit Supplemental Information Download | |
| Jun 24, 2019 | 1104 | Illumina Seminar Notice Download | |
| Jun 24, 2019 | 1103 | Sunnybrook Seminar Notice Download | |
| Jun 24, 2019 | 1098 | Affidavit of Christopher Butler Download | |
| Jun 24, 2019 | 17 | Motion to Submit Supplemental Information Download | |
| Jun 24, 2019 | 1100 | Mark Abramovitz et al. Download | |
| Jun 24, 2019 | 1102 | Bio-It World Download | |
| Jun 24, 2019 | 1101 | Jian-Bing Fan et al. Download | |
| Jun 24, 2019 | 1099 | Declaration of Mark Abramovitz Download | |
| Jun 24, 2019 | 1105 | Declaration of George Yu Download | |
| Jun 24, 2019 | 1108 | 2007-02-05 - Case No 1-04-cv-00901-JJF DI 357 Download | |
| Jun 24, 2019 | 1111 | Marina Bibikova et al. Download | |
| Jun 24, 2019 | 1112 | A Mitra et al. Download | |
| Jun 24, 2019 | 1106 | 2005-12-22 - Case No 1-04-cv-00901-JJF DI 140 Download | |
| Jun 24, 2019 | 1110 | Andrew C Haller et al. Download | |
| Jun 24, 2019 | 1113 | Natalie Stickle and Neil Winegarden Download | |
| Jun 24, 2019 | 1107 | 2006-02-09 - Case No 1-04-cv-00901-JJF DI 209 Download | |
| Jun 24, 2019 | 1109 | Declaration of Sylvia Hall-Ellis - Part 2 Download | |
| Jun 24, 2019 | 1109 | Declaration of Sylvia Hall-Ellis - Part 1 Download | |
| Jun 18, 2019 | 16 | Order - Conduct of the Proceedings - 37 CFR 42.5 Download | |
| Jun 17, 2019 | 15 | Notice of Deposition of Paul T. Spellman, Ph.D Download | |
| May 28, 2019 | 14 | Patent Owner's Objections to Evidence Download | |
| May 14, 2019 | 13 | Scheduling Order Download | |
| May 14, 2019 | 12 | Trial Instituted Document Download | |
| Apr 8, 2019 | 11 | PANEL CHANGE ORDER Conduct of the Proceedings 37 C.F.R. ¿¿ 42.5 Download | |
| Mar 19, 2019 | 10 | Patent Owner's Sur-Reply to Petitioner's Reply Download | |
| Mar 12, 2019 | 9 | Petitioner's Reply to Patent Owner's Preliminary Response Download | |
| Mar 5, 2019 | 8 | Conduct of the Proceeding Download | |
| Mar 4, 2019 | 3001 | Ex. 3001 Download | |
| Feb 15, 2019 | 7 | Patent Owner's Preliminary Response Download | |
| Feb 15, 2019 | 2002 | Wakelee, et al Optimizing First-Line Treatment Options for Patience with Advanced NSCLC Download | |
| Feb 15, 2019 | 2009 | U.S. Patent No. 8,880,350 Download | |
| Feb 15, 2019 | 2005 | National Comprehensive Cancer Network, Breast Cancer Clinical Practice Guidelines in Oncology Download | |
| Feb 15, 2019 | 2004 | Benson, et al American Society of Clinical Oncology Recommendations on Adjuvant Chemotherapy for Stage II Colon Cancer Download | |
| Feb 15, 2019 | 2001 | Horstmann, et al Risks and Benefits of Phase 1 Oncology Trials, 1991 through 2002 Download | |
| Feb 15, 2019 | 2013 | Von Hoff, Pilot Study Using Molecular Profiling of Patients Tumors to Find Potential Targets and Select Treatments for Their Refractory Cancers Download | |
| Feb 15, 2019 | 2011 | U.S. Patent No. 9,383,365 Download | |
| Feb 15, 2019 | 2014 | Doroshow, et al. Selecting Systemic Cancer Therapy One Patient at a Time Is There a Role for Molecular Profiling of Individual Patients With Advanced Solid Tumors? Download | |
| Feb 15, 2019 | 2010 | U.S. Patent No. 9,372,193 Download | |
| Feb 15, 2019 | 2008 | Declaration of Sandeep K. Reddy, submitted during prosecution of U.S. Patent App. 14/249,261 Download | |
| Feb 15, 2019 | 2006 | Leyland-Jones, Trastuzumab: Hopes and Realities Download | |
| Feb 15, 2019 | 2007 | National Comprehensive Cancer Network, Colon Cancer Clinical Practice Guidelines in Oncology Download | |
| Feb 15, 2019 | 2003 | Declaration of Michael Castro, submitted during prosecution of U.S. Patent App. 11/750,721 Download | |
| Feb 15, 2019 | 2012 | Seena Magowitz Foundation, Dr. Daniel Von Hoff Wins ASCO Award Download | |
| Nov 19, 2018 | 5 | Patent Owner's Mandatory Notices Download | |
| Nov 19, 2018 | 6 | Patent Owner's Power of Attorney Download | |
| Nov 15, 2018 | 4 | Notice of Accord Filing Date Download | |
| Nov 6, 2018 | 3 | Petition for Inter Partes Review of U.S. Patent No. 9,292,660 Download | |
| Nov 6, 2018 | 1060 | HUGO Gene Nomenclature Committee Symbol Report: ESR1, available at https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:3467 Download | |
| Nov 6, 2018 | 1069 | Andreas Gnirke et al., Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing, 27 Nature Biotechnology 182 (2009) Download | |
| Nov 6, 2018 | 1072 | Andreas Gnirke et al., Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing, 27 Nature Biotechnology 182, Supplementary Figures and Tables (2009) Download | |
| Nov 6, 2018 | 1073 | Ashish Gautam et al., RRM1-induced metastasis suppression through PTEN-regulated pathways, 22 Oncogene 2135 (2003) Download | |
| Nov 6, 2018 | 1080 | Degeng Wang, Discrepancy between mRNA and protein abundance: Insight from information retrieval process in computers, 32 Computational Biology & Chemistry 462 (2008) Download | |
| Nov 6, 2018 | 1057 | G. William Moore et al., A Prototype Internet Autopsy Database: 1625 Consecutive Fetal and Neonatal Autopsy Facesheets Spanning Twenty Years, 120 Archives Pathology Lab. Med. 782 (1996) Download | |
| Nov 6, 2018 | 1065 | Complaint Download | |
| Nov 6, 2018 | 1084 | U.S. Provisional Application No. 61/217,289 Download | |
| Nov 6, 2018 | 1051 | Masuko Katoh & Masaru Katoh, Bioinformatics for Cancer Management in the Post-Genome Era, 5 Technology in Cancer Research & Treatment 169 (2006) Download | |
| Nov 6, 2018 | 1088 | Tobias Sjoblom et al., The Consensus Coding Sequences of Human Breast and Colorectal Cancers, 314 Science 268, Supporting Material (2006), available at http://science.sciencemag.org/content/suppl/2006/10/24/1133427. DC1 Download | |
| Nov 6, 2018 | 1086 | U.S. Provisional Application No. 61/105,335 Download | |
| Nov 6, 2018 | 1047 | Marina Bibikova et al., Gene Expression Profiles in Formalin-Fixed, Paraffin-Embedded Tissues Obtained with a Novel Assay for Microarray Analysis, 50 Clinical Chemistry 2384 (2004) Download | |
| Nov 6, 2018 | 1079 | U.S. Patent No 8,768,629 (the 629 patent) Download | |
| Nov 6, 2018 | 1081 | Gerold Bepler, Pharmacogenomics: A reality or still a promise?, 54 Lung Cancer S3 (2006) Download | |
| Nov 6, 2018 | 1053 | Jian-Bing Fan et al., BeadArray-based solutions for enabling the promise of pharmacogenomics, 39 BioTechniques 583 (2005) Download | |
| Nov 6, 2018 | 1045 | HUGO Gene Nomenclature Committee Symbol Report: ERBB2, available at https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:3430 Download | |
| Nov 6, 2018 | 1095 | Olena Morozova & Marco A. Marra, Applications of next-generation sequencing technologies in functional genomics, 92 Genomics 255 (2008) Download | |
| Nov 6, 2018 | 1094 | Tobias Sjoblom et al., The Consensus Coding Sequences of Human Breast and Colorectal Cancers, 314 Science 268, Table S6 (2006), available at http://science.sciencemag.org/content/suppl/2006/10/24/1133427. DC1 Download | |
| Nov 6, 2018 | 1059 | Phillip G. Febbo & Geoffrey S. Ginsburg, Personalized diagnostic and therapeutic strategies in oncology, 2 Personalized Medicine 97 (2005) Download | |
| Nov 6, 2018 | 1071 | David J. Sugarbaker et al., Transcriptome sequencing of malignant pleural mesothelioma tumors, 105 PNAS 3521 (2008) Download | |
| Nov 6, 2018 | 1067 | Yardena Samuels et al., High Frequency of Mutations of the PIK3CA Gene in Human Cancers, 304 Science 554 (2004) Download | |
| Nov 6, 2018 | 1063 | Dan L. Longo, Imatinib Changed Everything, 376 New England J. Med. 982 (2017) Download | |
| Nov 6, 2018 | 1054 | U.S. Patent No. 9,092,392 (the 392 patent) Download | |
| Nov 6, 2018 | 1091 | Tobias Sjoblom et al., The Consensus Coding Sequences of Human Breast and Colorectal Cancers, 314 Science 268, Table S3 (2006), available at http://science.sciencemag.org/content/suppl/2006/10/24/1133427. DC1 Download | |
| Nov 6, 2018 | 1070 | Timothy Ley et al., DNA sequencing of a cytogenetically normal acute myeloid leukemia genome, 456 Nature 66 (2008) Download | |
| Nov 6, 2018 | 1052 | David Stipp, Gene Chip Breakthrough, Fortune Magazine, Mar. 31, 1997, at 56 Download | |
| Nov 6, 2018 | 1061 | NIH National Cancer Institute, How Imatinib Transformed Leukemia Treatment and Cancer Research, (updated Apr. 11, 2018) https://www.cancer.gov/research/progress/discovery/gleevec Download | |
| Nov 6, 2018 | 1092 | Tobias Sjoblom et al., The Consensus Coding Sequences of Human Breast and Colorectal Cancers, 314 Science 268, Table S4 (2006), available at http://science.sciencemag.org/content/suppl/2006/10/24/1133427. DC1 Download | |
| Nov 6, 2018 | 1087 | Tobias Sjoblom et al., The Consensus Coding Sequences of Human Breast and Colorectal Cancers, 314 Science 268 (2006) Download | |
| Nov 6, 2018 | 1076 | ThermoFisher Scientific, Overview of Immunohistochemistry (IHC) Download | |
| Nov 6, 2018 | 1058 | HUGO Gene Nomenclature Committee Symbol Report: CASP8, available at https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:1509 Download | |
| Nov 6, 2018 | 1048 | Marina Bibikova et al., Quantitative Gene Expression Profiling in Formalin-Fixed, Paraffin-Embedded Tissues Using Universal Bead Arrays, 165 American J. Pathology 1799 (2004) Download | |
| Nov 6, 2018 | 1050 | Jeffrey S. Ross & Geoffrey S. Ginsburg, The Integration of Molecular Diagnostics with Therapeutics: Implications for Drug Development and Pathology Practice, 119 Am. J. Clinical Pathology 26 (2003) (Ross) Download | |
| Nov 6, 2018 | 1090 | Tobias Sjoblom et al., The Consensus Coding Sequences of Human Breast and Colorectal Cancers, 314 Science 268, Tables S2A and S2B (2006), available at http://science.sciencemag.org/content/suppl/2006/10/24/1133427. DC1 Download | |
| Nov 6, 2018 | 1064 | Federico Cappuzzo et al., Clinical experience with gefitinib: An update, 58 Critical Reviews in Oncology/Hematology 31 (2006) Download | |
| Nov 6, 2018 | 1062 | Claudia Dreifus, Researcher Behind the Drug Gleevec, N.Y. Times (Nov. 2, 2009), at D4 Download | |
| Nov 6, 2018 | 1078 | HUGO Gene Nomenclature Committee Symbol Report: CTNNB1, available at https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:2514 Download | |
| Nov 6, 2018 | 1055 | David S. Wishart et al, DrugBank: a comprehensive resource for in silico drug discovery and exploration, 34 Nucleic Acids Research D668 (2006) Download | |
| Nov 6, 2018 | 1068 | Hong-Guang Xie & Felix W. Frueh, Pharmacogenomics steps toward personalized medicine, 2 Personalized Medicine 325 (2005) Download | |
| Nov 6, 2018 | 1085 | U.S. Provisional Application No. 61/170,565 Download | |
| Nov 6, 2018 | 1077 | HUGO Gene Nomenclature Committee Symbol Report: PIK3CA, available at https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:8975 Download | |
| Nov 6, 2018 | 1096 | HUGO Gene Nomenclature Committee Symbol Report- KIT, available at https-//www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC-6342 Download | |
| Nov 6, 2018 | 1049 | Jian-Bing Fan et al., A Versatile Assay for High-Throughput Gene Expression Profiling on Universal Array Matrices, 14 Genome Research 878 (2004) Download | |
| Nov 6, 2018 | 2 | Fee Authorization Download | |
| Nov 6, 2018 | 1089 | Tobias Sjoblom et al., The Consensus Coding Sequences of Human Breast and Colorectal Cancers, 314 Science 268, Table S1 (2006), available at http://science.sciencemag.org/content/suppl/2006/10/24/1133427. DC1 Download | |
| Nov 6, 2018 | 1083 | HUGO Gene Nomenclature Committee Symbol Report: RAF1, available at https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:9829 Download | |
| Nov 6, 2018 | 1074 | U.S. Patent Publication No. 2008/0014146 (Von Hoff) Download | |
| Nov 6, 2018 | 1046 | Business Wire, Illumina Launches DASL Assay and Cancer Panel for Gene Expression Profiling of Paraffin-Embedded Samples (Jan. 13, 2005) Download | |
| Nov 6, 2018 | 1082 | HUGO Gene Nomenclature Committee Symbol Report: BRAF, available at https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:1097 Download | |
| Nov 6, 2018 | 1093 | Tobias Sjoblom et al., The Consensus Coding Sequences of Human Breast and Colorectal Cancers, 314 Science 268, Table S5 (2006), available at http://science.sciencemag.org/content/suppl/2006/10/24/1133427. DC1 Download | |
| Nov 6, 2018 | 1056 | Timothy K. Egan, Monitoring Patients Undergoing Cancer Therapy, 31 Lab. Med. 666 (2000) Download | |
| Nov 6, 2018 | 1075 | Alberto Bardelli & Victor E. Velculescu, Mutational analysis of gene families in human cancer, 15 Current Opinion in Genetics & Development 5 (2005) Download | |
| Nov 6, 2018 | 1097 | HUGO Gene Nomenclature Committee Symbol Report- KRAS, available at https-//www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC-6407 Download | |
| Nov 6, 2018 | 1038 | S. Forbes et al., COSMIC 2005, 94 British J. Cancer 318 (2006) Download | |
| Nov 6, 2018 | 1009 | Charles Sawyers, Targeted cancer therapy, 432 Nature 294 (2004) Download | |
| Nov 6, 2018 | 1034 | Jeremy Gollub et al., The Stanford Microarray Database - data access and quality assessment tools, 31 Nucleic Acids Research 94 (2003) Download | |
| Nov 6, 2018 | 1005 | Illumina Gene Expression Profiling, Technical Bulletin, RNA Profiling with the DASL Assay (2005) (Illumina) Download | |
| Nov 6, 2018 | 1012 | Jackson B. Gibbs, Anticancer drug targets: growth factors and growth factor signaling, 105 J. Clinical Investigation 9 (2000) Download | |
| Nov 6, 2018 | 1020 | ClinicalTrials.gov, Study of TARCEVA (Erlotinib) as Adjuvant Treatment for Locally Advanced Head and Neck Squamous Cell Carcinoma, available at https-//clinicaltrials.gov/ct2/show/NCT01515137 Download | |
| Nov 6, 2018 | 1008 | Robert Langreth and Michael Waldholz, New Era of Personalized Medicine Targeting Drugs For Each Unique Genetic Profile, 4 The Oncologist 426 (1999) Download | |
| Nov 6, 2018 | 1040 | Timothy R. Hughes et al., Functional Discovery via a Compendium of Expression Profiles, 102 Cell 109 (2000) Download | |
| Nov 6, 2018 | 1018 | Tarceva (erlotinib) Prescribing Information (Nov. 18, 2004) Download | |
| Nov 6, 2018 | 1017 | Iressa (gefitinib) Prescribing Information (May 2, 2003) Download | |
| Nov 6, 2018 | 1015 | Herceptin (trastuzumab) Prescribing Information (Sept. 1998) Download | |
| Nov 6, 2018 | 1023 | Erbitux (cetuximab) Prescribing Information (Feb. 12, 2004) Download | |
| Nov 6, 2018 | 1043 | Xiaojun Zhao et al., Homozygous Deletions and Chromosome Amplifications in Human Lung Carcinomas Revealed by Single Nucleotide Polymorphism Array Analysis, 65 Cancer Research 5561 (2005) Download | |
| Nov 6, 2018 | 1024 | Affidavit of Christopher Butler Download | |
| Nov 6, 2018 | 1035 | Alexander Statnikov et al., GEMS: A System for Automated Cancer Diagnosis and Biomarker Discovery from Microarray Gene Expression Data, 74 International J. Med. Informatics 491 (2005) Download | |
| Nov 6, 2018 | 1033 | H. Parkinson, ArrayExpress a public repository for microarray gene expression data at the EBI, 33 Nucleic Acids Research D553 (2005) Download | |
| Nov 6, 2018 | 1032 | Daniel R. Rhodes et al., Oncomine 3.0: Genes, Pathways, and Networks in a Collection of 18,000 Cancer Gene Expression Profiles, 9 Neoplasia 166 (2007) Download | |
| Nov 6, 2018 | 1041 | U.S. Provisional Patent Application No. 60/747,645 Download | |
| Nov 6, 2018 | 1001 | U.S. Patent No. 9,292,660 to Von Hoff et al. (660 patent) Download | |
| Nov 6, 2018 | 1016 | S. Scholl, Targeting HER2 in Other Tumor Types, 12 Annals Oncology S81 (2001) Download | |
| Nov 6, 2018 | 1014 | Gleevec (imatinib mesylate) Prescribing Information (Jan. 2002) Download | |
| Nov 6, 2018 | 1028 | Thomas M. Daly et al., Precision Profiling and Components of Variability Analysis for Affymetrix Microarray Assays Run in a Clinical Context, 7 J. Molecular Diagnostics 404 (2005) Download | |
| Nov 6, 2018 | 1011 | Genomics and Personalized Medicine Act of 2006, S. 3822, 109th Cong. Download | |
| Nov 6, 2018 | 1039 | Justin Lamb et al., The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease, 313 Science 1929 (2006) Download | |
| Nov 6, 2018 | 1002 | Declaration of Paul T. Spellman, Ph.D. Download | |
| Nov 6, 2018 | 1031 | Daniel R. Rhodes et al., Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression, 25 PNAS 9309 (2004) Download | |
| Nov 6, 2018 | 1025 | Erbitux (cetuximab) Prescribing Information (Mar. 1, 2006) Download | |
| Nov 6, 2018 | 1026 | Jane E. Staunton et al., Chemosensitivity prediction by transcriptional profiling, 98 PNAS 10787 (2001) Download | |
| Nov 6, 2018 | 1044 | HUGO Gene Nomenclature Committee Symbol Report: EGFR, available at https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:3236 Download | |
| Nov 6, 2018 | 1037 | X. Chen et al., TTD: Therapeutic Target Database, 30 Nucleic Acids Research 412 (2002) Download | |
| Nov 6, 2018 | 1003 | File History Excerpt Download | |
| Nov 6, 2018 | 1007 | Amy L. McDoniels-Silvers et al., Differential Expression of Critical Cellular Genes in Human Lung Adenocarcinomas and Squamous Cell Carcinomas in Comparison to Normal Lung Tissues, 4 Neoplasia 141 (2002) Download | |
| Nov 6, 2018 | 1004 | PCT Publication No. WO 03/017038 (published Feb. 27, 2003) (Lu) Download | |
| Nov 6, 2018 | 1010 | NHGRI Seeks Next Generation of Sequencing Technologies (Oct. 14, 2004), https://www.genome.gov/12513210/ Download | |
| Nov 6, 2018 | 1042 | Oxford Dictionary of Biochemistry and Molecular Biology (Oxford University Press, 2d ed. 2006) Download | |
| Nov 6, 2018 | 1036 | C.J. Zheng et al., TRMP: a database of therapeutically relevant multiple pathways, 20 Bioinformatics 2236 (2004) Download | |
| Nov 6, 2018 | 1021 | NCI Drug Dictionary, https-//www.cancer.gov/publications/dictionaries/cancer-drug/def/cetuximab Download | |
| Nov 6, 2018 | 1027 | Atul J. Butte et al., Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks, 97 PNAS 12182 (2000) Download | |
| Nov 6, 2018 | 1006 | U.S. Patent Publication No. 2002/0150966 (Muraca) Download | |
| Nov 6, 2018 | 1 | Foundation Medicine, Inc. Power of Attorney Download | |
| Nov 6, 2018 | 1022 | Henry Q. Xiong & James L. Abbruzzese, Epidermal growth factor receptor-targeted therapy for pancreatic cancer, 29 Seminars in Oncology 31 (2002) Download | |
| Nov 6, 2018 | 1019 | James Moyer et al., Induction of Apoptosis and Cell Cycle Arrest by CP-358,774, an Inhibitor of Epidermal Growth Factor Receptor Tyrosine Kinase, 57 Cancer Research 4838 (1997) Download | |
| Nov 6, 2018 | 1013 | Nida Iqbal & Naveed Iqbal, Imatinib- A Breakthrough of Targeted Therapy in Cancer, Chemotherapy Research & Practice 1 (2014) Download | |
| Nov 6, 2018 | 1030 | Daniel R. Rhodes et al., Oncomine- A Cancer Microarray Database and Integrated Data-Mining Platform, 6 Neoplasia 1, 1 (2004) Download | |
| Nov 6, 2018 | 1029 | Thomas Jarvie, Next generation sequencing technologies, 2 Drug Discovery Today- Technologies 255 (2005) Download |
