Date Field | Doc. No. | Party | Description |
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Nov 13, 2019 | 52 | | Petitioner's Notice of Appeal Download |
Nov 13, 2019 | 53 | | Notice of Appeal/Cross-Appeal Download |
Sep 11, 2019 | 51 | | Termination Decision Document Download |
Jun 27, 2019 | 50 | | Hearing Transcript Download |
Jun 27, 2019 | 49 | | Hearing Transcript Download |
Jun 4, 2019 | 48 | | Patent Owner's Notice of Objection to Demonstrative Exhibits Download |
May 24, 2019 | 47 | | ORDER
Petitioner’s Unopposed Motion for
Pro Hac Vice Admission of Morgan Chu
37 C.F.R. § 42.10 Download |
May 23, 2019 | 46 | | Petitioner's Updated Mandatory Notice Download |
May 16, 2019 | 45 | | ORDER Trial Hearing Download |
May 15, 2019 | 42 | | Motion for PHV Admission of Morgan Chu Download |
May 15, 2019 | 43 | | Supplemental Power of Attorney Download |
May 15, 2019 | 44 | | Petitioner's Updated Exhibit List Download |
May 15, 2019 | 1027 | | Ex 1027 Chu Declaration iso PHV Motion Download |
May 14, 2019 | 1019 | | Ex 1019 (Replacement) Thompson Deposition Transcript-Vol.1 Download |
May 14, 2019 | 1020 | | Ex 1020 (Replacement) Thompson Deposition Transcript-Vol.2 Download |
May 10, 2019 | 39 | | Patent Owner's Request for Oral Argument Download |
May 10, 2019 | 40 | | Petitioner's Request for Oral Hearing Download |
May 10, 2019 | 41 | | Petitioner's Sur-Reply to PO's Contingent Motion to Amend Download |
May 8, 2019 | 3002 | | Ex. 3002 Download |
May 8, 2019 | 38 | | Order - Conduct of the Proceeding - 37 CFR 42.5 Download |
May 8, 2019 | 3001 | | Ex. 3001 Download |
May 3, 2019 | 37 | | Patent Owner's Updated Exhibit List Download |
May 3, 2019 | 2057 | | EX2057 - Hearing Transcript Download |
May 1, 2019 | 36 | | Notice of Filing Transcript and Petitioner's Updated Exhibit List Download |
May 1, 2019 | 1026 | | Ex 1026 Hearing Transcript Download |
Apr 24, 2019 | 35 | | Petitioner's Objections to Evidence in PO's Sur-Reply Download |
Apr 17, 2019 | 2056 | | EX2056 - April 2, 2019 Email from Board Download |
Apr 17, 2019 | 2049 | | EX2049 - WO2013090648 Download |
Apr 17, 2019 | 2047 | | EX2047 - WO2010088537 Download |
Apr 17, 2019 | 2051 | | EX2051 - WO2017223135 Download |
Apr 17, 2019 | 2048 | | EX2048 - Sedic 2017 LNP Safety Download |
Apr 17, 2019 | 33 | | Patent Owner's Reply to Opposition to Motion to Amend Download |
Apr 17, 2019 | 2055 | | EX2055 - Janoff Deposition Transcript - April 2019 Download |
Apr 17, 2019 | 34 | | Patent Owner's Sur-Reply Download |
Apr 17, 2019 | 2046 | | EX2046 - Table of Formulations Download |
Apr 17, 2019 | 2052 | | EX2052 - WO2018232357 Download |
Apr 17, 2019 | 2050 | | EX2050 - Bahl 2017 Mol Ther Influenza Download |
Apr 2, 2019 | 32 | | Amended Notice of Deposition of Dr. Janoff Download |
Mar 29, 2019 | 31 | | Patent Owner's Notice of Objection to Evidence Download |
Mar 28, 2019 | 30 | | Notice of Deposition of Dr. Janoff Download |
Mar 22, 2019 | 28 | | Petitioner's Reply to Patent Owner Response Download |
Mar 22, 2019 | 29 | | Petitioner's Opposition to PO's Contingent Motion to Amend Download |
Mar 22, 2019 | 1022 | | Ex 1022 IPR2018-00739 Janoff Dec ISO Opp. to MTA Download |
Mar 22, 2019 | 1025 | | Ex 1025 Decision on Appeal Download |
Mar 22, 2019 | 1024 | | Ex 1024 Kauffman 2015 Download |
Mar 22, 2019 | 1023 | | Ex 1023 IPR2018-00680 Patent Owner's Response Download |
Mar 22, 2019 | 1021 | | Ex 1021 Janoff Reply Declaration Download |
Mar 22, 2019 | 1020 | | Ex 1020 Thompson Deposition Transcript - vol.2 Download |
Mar 22, 2019 | 1019 | | Ex 1019 Thompson Deposition Transcript - vol.1 Download |
Mar 22, 2019 | 1019 | | Ex 1019 Thompson Deposition Transcript - vol.1 Download |
Mar 22, 2019 | 1020 | | Ex 1020 Thompson Deposition Transcript - vol.2 Download |
Jan 30, 2019 | 26 | | Corrected Patent Owner's Contingent Motion to Amend Download |
Jan 30, 2019 | 27 | | Notice of Deposition of Dr. Thompson Download |
Jan 30, 2019 | 2040 | | Corrected EX2040 - Thompson Declaration ISO Motion to Amend Download |
Dec 21, 2018 | 2026 | | EX2026 - Arbutus Press Release Download |
Dec 21, 2018 | 2042 | | EX2042 - Pat. App. No. 12424367 Download |
Dec 21, 2018 | 2016 | | EX2016 - Xconomy - Merck's Alan Sachs Download |
Dec 21, 2018 | 2009 | | EX2009 - Declaration of Dr. David Thompson Download |
Dec 21, 2018 | 2040 | | EX2040 - Thompson Declaration ISO Motion to Amend Download |
Dec 21, 2018 | 2012 | | EX2012 - 2007 Anal Chem Download |
Dec 21, 2018 | 2024 | | EX2024 - FDA press release Download |
Dec 21, 2018 | 2027 | | EX2027 - Patisiran Orange Book Download |
Dec 21, 2018 | 2014 | | EX2014 - Nature News 2003 Download |
Dec 21, 2018 | 2010 | | EX2010 - Thompson CV Download |
Dec 21, 2018 | 2022 | | EX2022 - Semple 2010 Nature Biotechnology (supplementary figures) Download |
Dec 21, 2018 | 2013 | | EX2013 - Final guidance liposome updated Download |
Dec 21, 2018 | 2011 | | EX2011 - ACS 2003 Download |
Dec 21, 2018 | 25 | | Patent Owner's Motion to Amend Download |
Dec 21, 2018 | 2018 | | EX2018 - US20130116307A1 Heyes Download |
Dec 21, 2018 | 2041 | | EX2041 - Prov. App. No. 61045228 Download |
Dec 21, 2018 | 2044 | | EX2044 - Pat. App. No. 13928309 Download |
Dec 21, 2018 | 2029 | | EX2029 - US9404127 Yaworski et al Download |
Dec 21, 2018 | 2025 | | EX2025 - European Medicines Agency Press Release Download |
Dec 21, 2018 | 2023 | | EX2023 - Ledford Nature News Download |
Dec 21, 2018 | 24 | | Patent Owner's Response Download |
Dec 21, 2018 | 2021 | | EX2021 - Semple 2010 Nature Biotechnology Download |
Dec 21, 2018 | 2017 | | EX2017 - US8236943 Lee Download |
Dec 21, 2018 | 2020 | | EX2020 - Janoff Patent Oath Download |
Dec 21, 2018 | 2033 | | EX2033 - Semple 2005 J. Pharmacology Experimental Therapeutics Download |
Dec 21, 2018 | 2034 | | EX2034 - Doxil product insert Download |
Dec 21, 2018 | 2028 | | EX2028 - Janoff deposition transcript Download |
Dec 21, 2018 | 2019 | | EX2019 - US20170307608A1 Bettencourt Download |
Dec 21, 2018 | 2043 | | EX2043 - Pat. App. No. 13253917 Download |
Dec 21, 2018 | 2045 | | EX2045 - Pat. App. No. 14462441 Download |
Dec 21, 2018 | 2015 | | EX2015 - Haussecker 2012 Molecular Therapy-Nucleic Acids Download |
Dec 21, 2018 | 2032 | | EX2032 - MacLachlan 2005 Advances in Genetics Download |
Dec 21, 2018 | 2040 | | EX2040 - Thompson Declaration ISO Motion to Amend Download |
Dec 12, 2018 | 23 | | Joint Stipulation to Modify the Scheduling Order Download |
Nov 16, 2018 | 22 | | Amended Notice of Deposition of Dr. Janoff Download |
Nov 12, 2018 | 21 | | Joint Stipulation to Modify the Scheduling Order Download |
Nov 1, 2018 | 20 | | Notice of Deposition of Dr. Janoff Download |
Oct 18, 2018 | 19 | | Conduct of the Proceeding
37 C.F.R. sec 42.5 Download |
Oct 18, 2018 | 18 | | ORDER
Conduct of the Proceeding
37 C.F.R. sec 42.5 Download |
Oct 4, 2018 | 2008 | | EX2008 - Transcript of October 2, 2018 Conference Call Download |
Oct 4, 2018 | 17 | | Patent Owner's Updated Exhibit List Download |
Sep 12, 2018 | 15 | | Institution of Inter Partes Review
35 U.S.C. sec 314(a) Download |
Sep 12, 2018 | 16 | | SCHEDULING ORDER
37 C.F.R. sec 42.5 Download |
Jul 20, 2018 | 14 | | Patent Owner Protiva Biotherapeutics, Inc.'s Updated Mandatory Notices Download |
Jul 19, 2018 | 13 | | Patent Owner Protiva Biotherapeutics, Inc.'s Updated Mandatory Notices Download |
Jun 14, 2018 | 2005 | | EX2005 - Huang Download |
Jun 14, 2018 | 2004 | | EX2004 - Tam Download |
Jun 14, 2018 | 2007 | | EX2007 - US7491409B1 Download |
Jun 14, 2018 | 2006 | | EX2006 - Janoff Download |
Jun 14, 2018 | 12 | | Patent Owner's Preliminary Response Download |
Jun 5, 2018 | 11 | | Order - 37 C.F.R. 42.10 Download |
May 31, 2018 | 2003 | | Ex. 2003- Reines Personal Statement Download |
May 31, 2018 | 9 | | Patent Owner's Updated Mandatory Notices Download |
May 31, 2018 | 8 | | Patent Owner's Motion for Pro Hac Vice Admission Download |
May 31, 2018 | 2001 | | Ex. 2001 - Reines Declaration Download |
May 31, 2018 | 2002 | | Ex. 2002 - In re Reines Download |
May 31, 2018 | 10 | | Patent Owner's Power of Attorney Download |
Mar 14, 2018 | 5 | | NOTICE OF FILING DATE ACCORDED TO PETITION
AND TIME FOR FILING PATENT OWNER PRELIMINARY RESPONSE Download |
Mar 14, 2018 | 6 | | Patent Owner's Mandatory Notices Download |
Mar 14, 2018 | 7 | | Patent Owner's Power of Attorney Download |
Mar 14, 2018 | 4 | | NOTICE OF FILING DATE ACCORDED TO PETITION & TIME FOR FILING PATENT OWNER PRELIMINARY RESPONSE Download |
Mar 14, 2018 | 3 | | Notice of Accord Filing Date Download |
Mar 5, 2018 | 2 | | '435 Petition Download |
Mar 5, 2018 | 1 | | Power of Attorney Download |
Mar 5, 2018 | 1001 | | Ex 1001 US Patent No. 9,364,435 Download |
Mar 5, 2018 | 1010 | | Ex 1010 Heyes, James et al., "Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids," 107 Journal of Controlled Release 276-87 (2005) Download |
Mar 5, 2018 | 1003 | | Ex 1003 US Publication No. 2006/0134189 Download |
Mar 5, 2018 | 1005 | | Ex 1005 Lin, Alison J., "Three-Dimensional Imaging of Lipid Gene-Carriers: Membrane Charge Density Controls Universal Transfection Behavior in Lamellar Cationic Liposome-DNA Complexes, 84 Biophysical Journal, pp. 3307-16 (2003) Download |
Mar 5, 2018 | 1007 | | Ex 1007 Janoff Declaration Download |
Mar 5, 2018 | 1004 | | Ex 1004 US Publication 2006/0240554 Download |
Mar 5, 2018 | 1002 | | Ex 1002 WO 2005/007196 Download |
Mar 5, 2018 | 1015 | | Ex 1015 Excerpts from '069 Patent File History Download |
Mar 5, 2018 | 1014 | | Ex 1014 US Publication No. 2006/0008910 Download |
Mar 5, 2018 | 1012 | | Ex 1012 US Patent No. 7,939,505 Download |
Mar 5, 2018 | 1006 | | Ex 1006 Ahmad, Ayesha et al., "New multivalent cationic lipids reveal bell curve for transfection efficiency versus membrane charge density: lipid-DNA complexes for gene delivery, 7 J Gene Med, pp. 739-48 (2005) Download |
Mar 5, 2018 | 1016 | | Ex 1016 '435 Patent File History Download |
Mar 5, 2018 | 1011 | | Ex 1011 US Patent No. 5,753,613 Download |
Mar 5, 2018 | 1017 | | Ex 1017 US Patent No. 5,264,618 Download |
Mar 5, 2018 | 1013 | | Ex 1013 US Publication No. 2007/0042031 Download |
Mar 5, 2018 | 1018 | | Ex 1018 Janoff CV Download |
Mar 5, 2018 | 1008 | | Ex 1008 Gao, Xiang et al., "Nonviral Gene Delivery: What We Know and What Is Next," AAPS Journal Article 9, pp. E92-E104 (2007) Download |
Mar 5, 2018 | 1009 | | Ex 1009 Bennett, Michael J. et al., "Cholesterol Enhances Cationic Liposome-Medicated DNA Transfection of Human Respiratory Epithlial Cells, 15 Bioscience Report, pp. 47-53 (1995) Download |