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Case number IPR2017-01488

Pfizer, Inc. v. Genentech, Inc. > Documents

Date Field Doc. No.PartyDescription
Dec 19, 2018 89 Order Granting Patent Owner's Renewed Motion to Seal Download
Dec 13, 2018 2006 Ex 2006 Genentech Notebook 11162 John Brady PUBLIC Download
Dec 13, 2018 88 Renewed Motion to Seal Download
Dec 13, 2018 2002 Ex 2002 Genentech Notebook 10823 Leonard Presta PUBLIC Download
Dec 13, 2018 2005 Ex 2005 Genentech Notebook 10840 John Brady PUBLIC Download
Dec 13, 2018 2001 Ex 2001 Genentech Notebook 10098 Leonard Presta PUBLIC Download
Nov 29, 2018 87 Final Written Decision Download
Sep 25, 2018 86 Petitioner Pfizer's Updated Mandatory Notices Download
Sep 19, 2018 85 Patent Owner's Updated Mandatory Notice Download
Aug 2, 2018 84 Hearing Transcript Download
Jul 13, 2018 79 Patent Owner's Objections to Demonstratives Download
Jul 13, 2018 81 Granting Petitioner's Unopposed Motion for Pro Hac Vice Admission of Sharick Naqi 37 C.F.R. sec. 42.10 Download
Jul 13, 2018 80 Petitioners Objections to Patent Owners Demonstrative Exhibits Download
Jul 13, 2018 82 Petitioners Updated Exhibit List Download
Jul 13, 2018 2060 Transcript of Conference Call dated June 19, 2018 Download
Jul 13, 2018 83 Patent Owner's Updated Exhibit List Download
Jul 12, 2018 77 Petitioner¿¿¿s Motion for Pro Hac Vice Admission of Sharick Naqi Download
Jul 12, 2018 78 Petitioner Pfizers Updated Mandatory Notices Download
Jul 12, 2018 1212 Declaration of Sharick Naqi in Support of Petitioner¿¿¿s Motion for the Pro Hac Vice Admission Download
Jul 11, 2018 76 Amending Grant of Request for Oral Argument Download
Jul 11, 2018 3003 Exhibit 3003 Download
Jul 10, 2018 75 Petitioners Reply in Support of Their Motion to Exclude Evidence Download
Jul 10, 2018 74 Patent Owner's Reply ISO Motion to Exclude Download
Jul 6, 2018 73 Petitioners Opposition to Patent Owners Motion to Strike Pursuant to Paper No. 60 Download
Jul 3, 2018 70 Petitioners Opposition to Patent Owners Motion to Exclude Evidence Download
Jul 3, 2018 71 Petitioners' Responses to Patent Owner¿¿¿s Observations on Cross-Examination of Jefferson Foote, Ph.D Download
Jul 3, 2018 72 Patent Owner's Opposition to Petitioners' Motion to Exclude Download
Jun 29, 2018 69 Granting Request for Oral Argument 37 C.F.R. § 42.70 Download
Jun 29, 2018 3002 Ex 3002 Download
Jun 22, 2018 65 Petitioners Request for Oral Argument Download
Jun 22, 2018 68 Petitioners Motion to Exclude Evidence [PUBLIC] Download
Jun 22, 2018 63 Patent Owner's Motion to Exclude Evidence Download
Jun 22, 2018 66 Petitioners Motion to Seal Download
Jun 22, 2018 61 Patent Owner's Motion to Strike Download
Jun 22, 2018 2059 Foote Deposition Transcript Download
Jun 22, 2018 62 Patent Owner's Request for Oral Argument Download
Jun 22, 2018 64 Patent Owner's Motion for Observations on Cross-Exam of Foote Download
Jun 21, 2018 60 Authorizing Briefing on Motion to Strike 37 C.F.R. § 42.5 Download
Jun 6, 2018 59 Patent Owner's Notice of Deposition of Foote Download
Jun 4, 2018 58 Patent Owner's Objection to Evidence Download
May 25, 2018 55 Petitioners Evidentiary Objections Download
May 25, 2018 57 Petitioners Reply to Patent Owners Response (PUBLIC) Download
May 25, 2018 54 Petitioners Motion to Seal Download
May 25, 2018 1194 Kolbinger, et al., Humunization of a Mouse Anti-Human IgE Antibody: A Potential Therapeutic for IgE-Mediated Allergies, 6(8) PROTEIN ENGINEERING 971¿¿¿980 (1993) Download
May 25, 2018 1197 Deposition Transcript of Ian A. Wilson, dated April 21, 2018 Download
May 25, 2018 1203 Reply Declaration of Christopher Lowden Download
May 25, 2018 1208 Mathieson et al., Monoclonal Antibody Therapy in Systemic Vasculitis, 323(4) NEW ENG. J.MED. 250-254 (1990). Download
May 25, 2018 1211 Havrdova, et. al., Alemtuzumab in the Treatment of Multiple Sclerosis: Key Clinical Trial Results and Considerations for Use, 8(1) THERAPEUTIC ADVANCES IN NEUROLOGICAL. DISORDERS 31-45 (2015). Download
May 25, 2018 1200 Deposition Transcript of Irene Loeffler, dated May 1, 2018 Download
May 25, 2018 1201 Deposition Transcript of John B. Ridgway Brady, dated April 27, 2018 Download
May 25, 2018 1207 Hale et al., Remission Induction in Non-Hodgkin Lymphoma with Reshaped Human Monoclonal Antibody Campath-1H, 332 LANCET 1394-1399 (1988). Download
May 25, 2018 1193 Foote, Humanized Antibodies [Foote Dep Ex] Download
May 25, 2018 1196 Presta, Humanized Monoclonal Antibodies, 29 Ann. Rep. in Med. Chemistry 317-24 (1994) Download
May 25, 2018 1204 Reply Declaration of Benjamin Lasky Download
May 25, 2018 1202 Reply Declaration of Jefferson Foote Download
May 25, 2018 1199 Deposition Transcript of Leonard G. Presta, dated May 1, 2018 Download
May 25, 2018 1198 Deposition Transcript of Paul J. Carter, dated April 27, 2018 Download
May 25, 2018 1195 DAVID J. KING, APPLICATIONS AND ENGINEERING OF MONOCLONAL ANTIBODIES (1998) Download
May 25, 2018 1210 Brown, Jr. et al., Anti-Tac-H, a Humanized Antibody to the Interleukin 2 Receptor Prolongs Primate Cardiac Allograft Survival, 88 PROC. NAT¿¿¿L. ACAD. SCI. U.S. 2663-2667 (1991). Download
May 25, 2018 1206 Foote & Winter, Antibody Framework Residues Affecting the Conformation of the Hypervariable Loops, 224 J.MOLECULAR BIOLOGY 487-499 (1991). Download
May 25, 2018 1205 Library of Congress Copyright Record for Presta ¿¿¿94 Download
May 25, 2018 1209 Kyle et al., Humanized Monoclonal Antibody Treatment in Rheumatoid Arthritis, 18(11) J. RHEUMATOLOGY 1737-1738 (1991). Download
May 18, 2018 53 Joint Notice of Stipulation to Revise Schedule Download
Apr 16, 2018 51 Petitioner Pfizer¿¿¿s Notice of Deposition of Dr. Leonard G. Presta Download
Apr 16, 2018 52 Petitioner Pfizers Notice of Deposition of Irene Loeffler Download
Apr 13, 2018 50 Notice of Deposition of John R. Brady Download
Apr 13, 2018 49 Notice of Deposition of Dr. Paul J. Carter Download
Apr 9, 2018 48 Petitioner Pfizers Notice of Deposition of Dr. Ian A. Wilson Under C.F.R. 42.53 Download
Apr 2, 2018 47 Patent Owner's Updated Mandatory Notice Download
Mar 15, 2018 46 Petitioner Pfizers Objections To Admissibility Of Evidence Download
Mar 8, 2018 2052 Trail Transcript - Sinomab Bio. v. Immunomedics Download
Mar 8, 2018 2039 Foote Deposition Transcript Download
Mar 8, 2018 2051 Man Sung Co - J. Immunology 1992 Download
Mar 8, 2018 45 Patent Owner's Response Download
Mar 8, 2018 2053 Brekke - Nature Reviews 2003 Download
Mar 8, 2018 2058 Redline of Ball / Buss Declarations IPR2016-01694 Download
Mar 8, 2018 2045 Bondi - J. Physical Chemistry 1964 Download
Mar 8, 2018 2043 US Patent No. 7560111 Download
Mar 8, 2018 2041 Wilson Expert Declaration Download
Mar 8, 2018 43 Motion to Seal Download
Mar 8, 2018 2042 US Patent No. 7375193 Download
Mar 8, 2018 2054 Waldmann - Science 1991 Download
Mar 8, 2018 2057 About HNCs and HNDs Download
Mar 8, 2018 2040 Buss Deposition Transcript Download
Mar 8, 2018 2044 Presta - J. Immunology 1993 Download
Mar 8, 2018 2056 Ball Declaration IPR2016-01694 Download
Mar 8, 2018 2055 Winter - TiPS 1993 Download
Feb 22, 2018 42 Decision (IPR2017-02139) - Institution of Inter Partes Review and Grant of Motion for Joinder Download
Feb 2, 2018 41 Patent Owner's Second Updated Mandatory Notices Download
Feb 1, 2018 40 Petitioner Pfizers Updated Mandatory Notices Download
Jan 29, 2018 39 ORDER Revising Due Date 7 Download
Jan 19, 2018 37 Patent Owner's Notice of Deposition of Jefferson Foote Download
Jan 19, 2018 38 Joint Notice of Stipulation of Due Date 1 and 2 Download
Jan 19, 2018 36 Patent Owner's Notice of Deposition of Timothy Buss Download
Jan 11, 2018 34 Decision - Institution of Inter Partes Review (republished as non-confidential) Download
Jan 11, 2018 35 Erratum (republished as non-confidential) Download
Dec 15, 2017 32 PO Objection to Evidence Download
Dec 15, 2017 31 Joint Statement re the Institution Decision Download
Dec 15, 2017 33 Petitioner's Objections to Admissibility of Evidence Download
Dec 15, 2017 30 Erratum Download
Dec 8, 2017 29 Petitioner's Updated Mandatory Notices Download
Dec 1, 2017 28 Case Management and Scheduling Order Download
Dec 1, 2017 27 Decision Institution of Inter Partes Review Download
Nov 29, 2017 26 Patent Owner's Updated Mandatory Notices Download
Nov 15, 2017 25 Decision - Grant of Patent Owners Motion to Seal and Entry of Stipulated Protective Order Download
Nov 15, 2017 24 Decision - Granting Petitioner's Unopposed Motions for Pro Hac Vice Admission of Sarah K. Tsou, Benjamin A. Lasky, Mark C. McLennan, and Christopher J. Citro Download
Nov 2, 2017 22 Petitioners Motion for the Pro Hac Vice Admission of Christopher J. Citro Download
Nov 2, 2017 23 Petitioners First Amended Appendix of Exhibits Download
Nov 2, 2017 20 Petitioners Motion for the Pro Hac Vice Admission of Benjamin A. Lasky Download
Nov 2, 2017 19 Petitioners Motion for the Pro Hac Vice Admission of Sarah K. Tsou Download
Nov 2, 2017 21 Petitioners Motion for the Pro Hac Vice Admission of Mark. C. McLennan Download
Nov 2, 2017 17 Petitioners Updated Power of Attorney Download
Nov 2, 2017 1191 Declaration of Mark. C. McLennan in Support of Petitioners Motion for the Pro Hac Vice Admission Download
Nov 2, 2017 18 Petitioners Updated Mandatory Notices Download
Nov 2, 2017 1189 Declaration of Sarah K. Tsou in Support of Petitioners Motion for the Pro Hac Vice Admission Download
Nov 2, 2017 1192 Declaration of Christopher J. Citro in Support of Petitioners Motion for the Pro Hac Vice Admission Download
Nov 2, 2017 1190 Declaration of Benjamin A. Lasky in Support of Petitioners Motion for the Pro Hac Vice Admission Download
Oct 20, 2017 16 Petitioner¿¿¿s Updated Mandatory Notices Download
Sep 27, 2017 3001 E-mail from Petitioner, Sept. 21, 2017 Download
Sep 27, 2017 15 Decision Granting Patent Owner's Unopposed Motions for Pro Hac Vice Admission of Daralyn J. Durie, Robert J. Gunther, Lisa J. Pirozzolo, Kevin S. Prussia, and Andrew J. Danford Download
Sep 27, 2017 14 Order - re Petitioner's Request for Authorization to Correct IPR2017-01489 Petition and to File Reply Briefs Download
Sep 22, 2017 2034 Declaration of Robert J. Gunther, Jr. in Support of Motion for Admission Pro Hac Vice Download
Sep 22, 2017 2038 Declaration of Andrew J. Danford in Support of Motion for Admission Pro Hac Vice Download
Sep 22, 2017 2035 Declaration of Daralyn J. Durie in Support of Patent Owner's Motion for Pro Hac Vice Admission Download
Sep 22, 2017 2037 Declaration of Kevin S. Prussia in Support of Motion for Admission Pro Hac Vice Download
Sep 22, 2017 2036 Declaration of Lisa J. Pirozzolo in Support of Motion for Admission Pro Hac Vice Download
Sep 22, 2017 9 Patent Owner's Unopposed Motion for Admission Pro Hac Vice of Daralyn J. Durie Download
Sep 22, 2017 10 Patent Owner's Unopposed Motion for Admission Pro Hac Vice of Robert J. Gunther, Jr. Download
Sep 22, 2017 11 Patent Owner's Unopposed Motion for Admission Pro Hac Vice of Lisa J. Pirozzolo Download
Sep 22, 2017 13 Patent Owner's Unopposed Motion for Admission Pro Hac Vice of Andrew J. Danford Download
Sep 22, 2017 12 Patent Owner's Unopposed Motion for Admission Pro Hac Vice of Kevin S. Prussia Download
Sep 5, 2017 2025 Ex 2025 Isaacs 1992 Download
Sep 5, 2017 2023 Ex 2023 Kalsi 1999 Download
Sep 5, 2017 2028 Ex 2028 Shepard 2008 Download
Sep 5, 2017 2022 Ex 2022 Bruggerman 1989 Download
Sep 5, 2017 2026 Ex 2026 Kabat 1987 Download
Sep 5, 2017 2031 EX 2031 Modified Default Standing Protective Order 1488_Redline Download
Sep 5, 2017 2020 Ex 2020 Carter 1992 Download
Sep 5, 2017 2018 Ex 2018 Brady Decl_PUBLIC Download
Sep 5, 2017 7 Patent Owner's Preliminary Response Download
Sep 5, 2017 2033 Ex 2033 Shearman Download
Sep 5, 2017 2027 Ex 2027 Tramontano 1990 Download
Sep 5, 2017 2024 Ex 2024 Gorman 1991 Download
Sep 5, 2017 2029 Ex 2029 Excerpt from Roche Finance Report 2016 Download
Sep 5, 2017 2019 Ex 2019 Loeffler Declaration Pfizer 1488 Download
Sep 5, 2017 2030 Ex 2030__Modified Default Standing Protective Order and Certification 1488 Download
Sep 5, 2017 2016 Ex 2016 Presta Declaration PUBLIC Download
Sep 5, 2017 8 Patent Owner's Motion to Seal Download
Sep 5, 2017 2017 Ex 2017 Carter Declaration Pfizer_PUBIC Download
Sep 5, 2017 2021 Ex 2021 Presta 1997 Download
Sep 5, 2017 2032 Ex 2032 File History for US Patent Application No 07_715272 Download
Jun 13, 2017 4 Patent Owner's Mandatory Notices Download
Jun 13, 2017 5 Genentech Power of Attorney Download
Jun 5, 2017 3 Notice of Accord Filing Date Download
May 25, 2017 2 PFIZER, INC. POWER OF ATTORNEY Download
May 25, 2017 1096 U.S. Patent No. 5,677,171, Monoclonal Antibodies Directed to the HER2 Receptor Download
May 25, 2017 1081 Sheriff et al., Three-Dimensional Structure of an Antibody- Antigen Complex Download
May 25, 2017 1116 Padlan et al., Model Building Studies of Antigen-binding Sites: the Hapten Binding Site of MOPC-315 Download
May 25, 2017 1180 Library of Congress Copyright Record for Co 91 Download
May 25, 2017 1115 Poljak et al., The Three-Dimensional Structure of the Fab Fragment of A Human Myeloma Immunoglobulin at 2.0-Resolution, Download
May 25, 2017 1185 Miller, To Build a Better Mousetrap, Use Human Parts Download
May 25, 2017 1153 Library of Congress Copyright Record for King 85 Download
May 25, 2017 1103 Brient & Nisonoff, Quantitative Investigations of Idiotypic Antibodies. IV. Inhibition by Specific Haptens of the Reaction of Anti-Hapten Antibody with Its Anti-Idiotypic Antibody Download
May 25, 2017 1130 U.S. Patent No. 4,891,762 Download
May 25, 2017 1145 Library of Congress Copyright Record for Liu 87 Download
May 25, 2017 1044 Fukushige et al., Localization of a Novel v-erbB-Related Gene, c-erbB-2, on Human Chromosome 17 and its Amplification in a Gastric Cancer Cell Line Download
May 25, 2017 1096 U.S. Patent No. 5,677,171, Monoclonal Antibodies Directed to the HER2 Receptor Download
May 25, 2017 1159 Library of Congress Copyright Record for Davies & Metzger Download
May 25, 2017 1085 Satow et al., Phosphocholine Binding Immunogloubulin Fab McPC306 An X-ray Diffraction Study Download
May 25, 2017 1079 Kabat et al., Sequences of Proteins of Immunological Interest: Tabulation and Analysis of Amino Acid and Nucleic Acid Sequences of Precursor Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1090 Wilson & Goulding, A Biologists Guide to Principles and Techniques of Practical Biochemistry Download
May 25, 2017 1023 Prabakaran, The Quest for a Magic Bullet Download
May 25, 2017 1083 Saul et al., Preliminary Refinement and Structural Analysis of the Fab Fragment from Human Immunoglobulin New at 2.0 Resolution Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1004 Declaration of Mr. Buss in Support of Petition for Inter Partes Review of Patent No. 6,407,213 Download
May 25, 2017 1148 Library of Congress Copyright Record for Kirkman 89 Download
May 25, 2017 1082 Marquart et al., The Three-Dimensional Structure of Antibodie Download
May 25, 2017 1025 Cosimi Treatment of Acute Renal Allograft Rejection with OKT3 Monoclonal Antibody, Download
May 25, 2017 1155 Library of Congress Copyright Record for Coussens 85 Download
May 25, 2017 1106 Schroff et al., Human Anti-Murine Immunoglobulin Responses in Patients Receiving Monoclonal Antibody Therap Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1131 Wallick et al., Glycosylation of A VH Residue of a Monoclonal Antibody Against a(L-6) Dextran Increases its Affinity for Antigen Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1037 Hakimi et al., Reduced Immunogenicity and Improved Pharmacokinetics of Humanized ANTI-Tac in Cynomolgus Monkeys Download
May 25, 2017 1141 Library of Congress Copyright Record for Cosimi 81 Download
May 25, 2017 1163 Library of Congress Copyright Record for Verhoeyen 88 Download
May 25, 2017 1128 Co et al., Humanized Antibodies for Antiviral Therapy Download
May 25, 2017 1045 Slamon et al., Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/neu Oncogene, Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1164 Library of Congress Copyright Record for Riechmann 88 Download
May 25, 2017 1151 Library of Congress Copyright Record for Vincenti 98 Download
May 25, 2017 1040 Harris et al., Medical Progress: Breast Cancer Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1181 Library of Congress Copyright Record for Wallick 88 Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1 PETITION FOR INTER PARTES REVIEW OF U.S. PATENT NO. 6,407,213 UNDER 35 U.S.C. 311 AND 37 C.F.R. 42.100 Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1001 U.S. Patent No. 6,407,213 Download
May 25, 2017 1167 Library of Congress Copyright Record for Sheriff 87 Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1073 Winter et al., EP Publication Number 0239400, Recombinant Antibodies and Methods for Their Productions Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1157 Library of Congress Copyright Record for Hudziak 87 Download
May 25, 2017 1032 Liu et al., Chimeric Mouse-Human IgG1 Antibody that can Mediate Lysis of Cancer Cells Download
May 25, 2017 1182 Bodmer, International Publication No. WO 1989/01783 (published March 9, 1989) Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1146 Library of Congress Copyright Record for Jones 86 Download
May 25, 2017 1022 Kohler Continuous Cultures of Fused Cells Secreting Antibody of Predefined Specificity Download
May 25, 2017 1152 Library of Congress Copyright Record for Harris 92 Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1186 Library of Congress Copyright Record for Miller 98 Download
May 25, 2017 1093 Morin, From Oncogene to Drug: Development of Small Molecule Tyrosine Kinase Inhibitors as Anti-Tumor and Anti-Angiogenic Agents, Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1027 Jaffers et al., Monoclonal Antibody Therapy: Anti-Idiotypic and Non-Anti-Idiotypic Antibodies to OKT3 Arising Despite Intense Immunosuppression Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1143 Library of Congress Copyright Record for Jaffers 86 Download
May 25, 2017 1170 Library of Congress Copyright Record for Padlan 89 Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1113 Epp et al., The Molecular Structure of a Dimer Composed of the Variable Portions of the Bence-Jones Protein REI Refined at 2.0 Resolution Download
May 25, 2017 1127 Jones, Diffraction Methods for Biological Macromolecules. Interactive Computer Graphics: FRODO, 115 Methods Enzymology Download
May 25, 2017 1142 Library of Congress Copyright Record for OMTSG 85 Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1088 Kumar et al., Regulation of Phosphorylation of the c-erbB-2/HER2 Gene Product by Monoclonal Antibody and Serum Growth Factor(s) in Human Mammary Carcinoma Cells, Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1174 Library of Congress Copyright Record for Schroff 85 Download
May 25, 2017 1036 Waldmann et al., The Interleukin-2 Receptor: A Target for Monoclonal Antibody Treatment of Human T-Cell Lymphotrophic Virus I-Induced Adult T-Cell Leukemia Download
May 25, 2017 1031 Morrison et al., Chimeric Human Antibody Molecules: Mouse Antigen-Binding Domains With Human Constant Region Domains, Download
May 25, 2017 1042 Semba et al., A v-erbB-Related Protooncogene, c-erbB-2, is Distinct from the c-erbB-1 / Epidermal Growth Factor-Receptor Gene and is Amplified in a Human Salivary Gland Adenocarcinoma Download
May 25, 2017 1030 Protein Data Bank - Chronology Download
May 25, 2017 1039 SEER Stat Fact Sheets: Breast Cancer, National Cancer Institute, Download
May 25, 2017 1051 Tramontano et al., Framework Residue 71 is a Major Determinant of the Position and Conformation of the Second Hypervariable Region in the VH Domains of Immunoglobulins Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1058 Davies & Metzger, Structural Basics of Antibody Function Download
May 25, 2017 1178 Library of Congress Copyright Record for Suh 86 Download
May 25, 2017 1125 Furey et al., Structure of A Novel Bence-Jones Protein (Rhe) Fragment at 1.6¿¿ Resolution Download
May 25, 2017 1173 Library of Congress Copyright Record for Chanh 87 Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1034 Queen et al., A Humanized Antibody That Binds to the Interleukin 2 Receptor Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1026 Ortho Multicenter Transplant Study Group, A Randomized Clinical Trial of OKT3 Monoclonal Antibody for Acute Rejection of Cadveric Renal Transplants Download
May 25, 2017 1156 Library of Congress Copyright Record for Slamon 87 Download
May 25, 2017 1179 Library of Congress Copyright Record for Jones 85 Download
May 25, 2017 1158 Library of Congress Copyright Record for Chothia 89 Download
May 25, 2017 1029 Sikora, Monoclonal Antibodies in Oncology, Download
May 25, 2017 1024 Marks, The Story of Cesar Milstein and Monoclonal Antibodies: A Healthcare Revolution in the Making Download
May 25, 2017 1126 Segal et al., The Three-Dimensional Structure of a Phosphorylcholine-Binding Mouse Immunoglobulin Fab and the Nature of the Antigen Binding Site Download
May 25, 2017 1121 Suh et al., The Galactan-Binding Immunoglobulin Fab J539 Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1100 Colman et al., Three-Dimensional Structure of a Complex of Antibody with Influenza Virus Neuraminidase Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1102 Bender et al., Immunogenicity, Efficacy and Adverse Events of Adalimumab in RA Patients Download
May 25, 2017 1086 Herron et al., Three-Dimensional Structure of a Fluorescein-Fab Complex Crystallized in 2-Methyl-2,4-Pentanedio Download
May 25, 2017 1188 Declaration of Christopher Lowden Download
May 25, 2017 1068 Verhoeyen et al., Reshaping Human Antibodies: Grafting an Antilysozyme Activity, Download
May 25, 2017 1104 Koprowski et al., Human Anti-Idiotype Antibodies in Cancer Patients: Is the Modulation of the Immune Response Beneficial for the Patient Download
May 25, 2017 1168 Library of Congress Copyright Record for Saul 78 Download
May 25, 2017 1150 Library of Congress Copyright Record for Hakimi 91 Download
May 25, 2017 1089 Soomro et al., C-erbB-2 Expression in Different Histological Types of Invasive Breast Carcinoma Download
May 25, 2017 1183 Gorman, International Publication No. WO 1992/05274 (published April 2, 1992) Download
May 25, 2017 1071 Kurrle et al., EP Publication Number 0403156, Improved Monoclonal Antibodies Against the Human Alphabeta T-Cell Receptor, Their Production and Use Download
May 25, 2017 1105 Chanh et al., Monoclonal Anti-Idiotypic Antibody Mimics the CD4 Receptor and Binds Human Immunodeficiency Virus Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1187 Declaration of Amanda Hollis Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1050 Queen, International Publication No. WO 1990/07861 Download
May 25, 2017 1096 U.S. Patent No. 5,677,171, Monoclonal Antibodies Directed to the HER2 Receptor Download
May 25, 2017 1021 Hudziak p185HER2 Monoclonal Antibody Has Antiproliferative Effects In Vitro and Sensitizes Human Breast Tumor Cells to Tumor Necrosis Factor Download
May 25, 2017 1047 Hudziak et al., Increased Expression of the Putative Growth Factor Receptor p185HER2 Causes Transformation and Tumorigenesis of NIH 3T3 Cells. Download
May 25, 2017 1172 Library of Congress Copyright Record for Koprowski 84 Download
May 25, 2017 1028 Sears et al., Phase-I Clinical Trial of Monoclonal Antibody in Treatment of Gastrointestinal Tumours, Download
May 25, 2017 1184 Declaration of Karen Younkins Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1092 Capra & Kehoe, Variable Region Sequences of Five Human Immunoglobulin Heavy Chains of the VHIII Subgroup: Definitive Identification of Four Heavy Chain Hypervariable Regions, Download
May 25, 2017 1091 Edelman et al., The Covalent Structure of an Entire gG Immunoglobulin Molecule Download
May 25, 2017 1043 Coussens et al., Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene, Download
May 25, 2017 1096 U.S. Patent No. 5,677,171, Monoclonal Antibodies Directed to the HER2 Receptor Download
May 25, 2017 1041 King et al., Amplification of a Novel v-erbB Related Gene in a Human Mammary Carcinoma, Download
May 25, 2017 1149 Library of Congress Copyright Record for Waldamnn 93 Download
May 25, 2017 1096 U.S. Patent No. 5,677,171, Monoclonal Antibodies Directed to the HER2 Receptor Download
May 25, 2017 1069 Riechmann et al., Reshaping Human Antibodies for Therapy Download
May 25, 2017 1080 Bernstein et al., The Protein Data Bank: A Computer-based Archival File for Macromolecular Structures Download
May 25, 2017 1059 Amit et al., Three-Dimensional Structure of an Antigen-Antibody Complex at 2.8 Download
May 25, 2017 1003 Declaration of Dr. Foote in Support of Petition for Inter Partes Review of Patent No. 6,407,213 Download
May 25, 2017 1049 Chothia et al., Conformations of Immunoglobulin Hypervariable Regions, Download
May 25, 2017 1038 Vincenti et al., Interleukin 2 Receptor Blockade with Daclizumab to Prevent Acute Rejection in Renal Transplantation Download
May 25, 2017 1147 Library of Congress Copyright Record for Queen 89 Download
May 25, 2017 1062 Chothia & Lesk, Canonical Structures for the Hypervariable Regions of Immunoglobulins, Download
May 25, 2017 1154 Library of Congress Copyright Record for Semba 85 Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1129 Excel Trick, History of Microsoft Excel 1978-2013 Download
May 25, 2017 1046 Kraus et al., Overexpression of the EGF Receptor-Related Proto-Oncogene erbB-2 in Human Mammary Tumor Cell Lines by Different Molecular Mechanisms, Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1052 Kabat et al., Sequences of Proteins of Immunological Interest: Tabulation and Analysis of Amino Acid and Nucleic Acid Sequences of Precursors, V-Regions, C-Regions, J-Chain, T-Cell Receptor for Antigen, T-Cell Surface Antigens, b2-Microglubin Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1033 Jones et al., Replacing the Complementarity-Determining Regions in a Human Antibody With Those From a Mouse Download
May 25, 2017 1114 Mian, Structure, Function and Properties of Antibody Binding Sites Download
May 25, 2017 1048 Shepard et al., Monoclonal Antibody Therapy of Human Cancer: Taking the HER2 Protooncogene to the Clinic, Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1087 Padlan et al., Structure of an Antibody-Antigen Complex: Crystal Structure of the HyHEL-10 Fab-Lysozyme Complex, Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1160 Library of Congress Copyright Record for Amit 86 Download
May 25, 2017 1096 U.S. Patent No. 5,677,171, Monoclonal Antibodies Directed to the HER2 Receptor Download
May 25, 2017 1055 Kabat et al., Sequences of Proteins of Immunological Interest: Tabulation and Analysis of Amino Acid and Nucleic Acid Sequences of Precursors, V-Regions, C-Regions, J-Chain, T-Cell Receptor for Antigen, T-Cell Surface Antigens Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1063 Chothia et al., Domain Association in Immunoglobulin Molecules: The Packing of Variable Domain Download
May 25, 2017 1095 Patent Interference No. 105,744 Vol. 4 Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 4 Download
May 25, 2017 1144 Library of Congress Copyright Record for Morrison 84 Download
May 25, 2017 1035 Kirkman et al., Early Experience with Anti-Tac in Clinical Renal Transplantation, Download
May 25, 2017 1107 Abdou et al., Network Theory in Autoimmunity. In Vitro Suppression of Serum Anti-DNA by Anti-idiotypic Antibody in Systemic Lupus Erythematosus Download
May 25, 2017 1171 Library of Congress Copyright Record for Colman 87 Download
May 25, 2017 1097 Sambrook et al., Molecular Cloning: A Laboratory Manual Download
May 25, 2017 1002 File History for U.S. Patent No. 6,407,213 Vol. 10 Download
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