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Case number IPR2018-00402

MERCK SHARP & DOHME CORP. v. Microspherix LLC > Documents

Date Field Doc. No.PartyDescription
Jul 22, 2019 45 Notice of Appeal Download
Jul 8, 2019 44 Termination Decision Document Download
Apr 29, 2019 43 Hearing Transcript Download
Apr 4, 2019 42 JOINT OBJECTIONS TO DEMONSTRATIVE EXHIBITS Download
Apr 1, 2019 2153 Microspherix's Oral Hearing Demonstratives Download
Apr 1, 2019 1077 Petitioners' Demonstrative Exhibits Download
Mar 25, 2019 41 Petitioners¿¿¿ Reply to Patent Owner¿¿¿s Opposition to Motion to Exclude Evidence Download
Mar 20, 2019 40 Order - 37 U.S.C. 316(a)(10) and 37 C.F.R. 42.70 Download
Mar 15, 2019 2152 Email from Microspherix to Counsel for Merck enclosing supplemental exhibits 2078-2080 Download
Mar 15, 2019 39 Microspherix's Opposition to Petitioners' Motion to Exclude Download
Mar 12, 2019 38 Petitioners' Sur-Sur Reply Download
Mar 5, 2019 37 Petitioners' Motion to Exclude Evidence Download
Mar 5, 2019 35 Petitioners' Request for Oral Hearing Pursuant to 37 C.F.R. Section 42.70 Download
Mar 5, 2019 36 Petitioners' Request for Oral Argument Pursuant to 37.C.F.R. Section 42.70 Download
Mar 5, 2019 34 Patent Owner's Sur-Reply Download
Mar 5, 2019 33 Patent Owner's Request for Oral Hearing Download
Mar 5, 2019 2151 Letter to the Editor - Contraception Download
Mar 4, 2019 2150 2/27/2019 Telephonic Hearing Transcript Download
Feb 28, 2019 32 Conduct of Proceeding Download
Feb 9, 2019 2149 2/4/19 Telephonic Hearing Transcript Download
Feb 6, 2019 31 ORDER Conduct of Proceeding Download
Jan 31, 2019 30 Petitioner's Updated Mandatory Notices Download
Jan 31, 2019 29 Petitioner's Updated Power of Attorney Download
Jan 30, 2019 28 Patent Owner¿¿¿s Objections to Admissibility of Evidence Filed and Served with Petitioner¿¿¿s Reply Download
Jan 23, 2019 1071 Lantz, Ultrasound Characteristics of Subdermally Implanted Implanon¿¿¿ Contraceptive Rods, Contraception 56:323-27 (1997) (¿¿¿Lantz¿¿¿) Download
Jan 23, 2019 1067 Oloto, Norplant removal: a review, The British Journal of Family Planning vol. 21, no. 1 (Suppl), pp. 21-24 (1995) Download
Jan 23, 2019 1074 Physician¿¿¿s Desk Reference, 53rd Edition, pages 3344-48 (1999) Download
Jan 23, 2019 1075 Complete Prosecution History of U.S. Pat. App. No. 10/592725 (U.S. 8,722,037) Download
Jan 23, 2019 1072 Crist, Difficult Finding and Removing a Norplant¿¿ System Capsule, North Carolina Medical Journal, Vol. 55, No. 2, p. 76 (1994) Download
Jan 23, 2019 1064 Transcript of the Cross Examination of Patrick F. Kiser, Ph.D. (Dec. 13, 2018) Download
Jan 23, 2019 1065 Transcript of the Cross Examination of Patrick F. Kiser, Ph.D. (Dec. 14, 2018) Download
Jan 23, 2019 1073 L. Mascarenhas, Insertion and Removal of Implanon¿¿, Contraception 58:79S-83S (1998) (¿¿¿Mascarenhas 1998¿¿¿) Download
Jan 23, 2019 1066 Croxatto, The Pharmacodynamics and Efficacy of Implanon¿¿, Contraception 58:91S-97S (1998) Download
Jan 23, 2019 1070 Sarma, Removal of Deeply Inserted, Nonpalpable Levonorgestrel (Norplant¿¿) Implants, Contraception 53:159-61 (1996) (¿¿¿Sarma¿¿¿) Download
Jan 23, 2019 1076 U.S. Patent No. 6,197,324 to Crittenden ("Crittenden") Download
Jan 23, 2019 1069 Thurmond, Localization of Contraceptive Implant Capsules for Removal, Radiology 193:580-81 (1994) (¿¿¿Thurmond¿¿¿) Download
Jan 23, 2019 1063 Microspherix LLC v. Merck Sharp & Dohme Corp. et al., C.A. No. 2:17-cv-03984-CCC-JBC, Plaintiff¿¿¿s Preliminary Disclosure of Asserted Claims and Infringement Contentions Against Defendants, served March 7, 2018 Download
Jan 23, 2019 1068 Twickler, Imaging of the levonorgestrel implantable contraceptive device, 167 Am. J. Obstet. Gynecol. 2, 572-73 (1992) (¿¿¿Twickler¿¿¿) Download
Jan 23, 2019 27 Petitioner's Reply Download
Nov 8, 2018 26 Notice of Deposition of Patrick F. Kiser, Ph.D. Download
Oct 30, 2018 25 Petitioners' Objections to Patent Owner's Exhibits Download
Oct 23, 2018 2094 Brem 1996 Download
Oct 23, 2018 2145 Ren 2002 Download
Oct 23, 2018 2115 Ortiz 2007 Download
Oct 23, 2018 2107 Neisuler 1970 Download
Oct 23, 2018 2112 Palo 1997 Download
Oct 23, 2018 2131 US20030010929A1 Download
Oct 23, 2018 2117 Khatri 2015 Download
Oct 23, 2018 2110 Piiroinen 1972 Download
Oct 23, 2018 2090 Langer 1980 (Chem Eng Commun) Download
Oct 23, 2018 2109 Khan 1994 Download
Oct 23, 2018 2113 Bruwer 1976 Download
Oct 23, 2018 2135 Langer 1981b (Trans Am Soc Artif Intern Organs) Download
Oct 23, 2018 2085 Langer 2000 (Acc Chem Res) Download
Oct 23, 2018 2086 Langer and Brem (Lesniak) Download
Oct 23, 2018 2143 US6599448 Download
Oct 23, 2018 2142 Langer Dep. Tr. Download
Oct 23, 2018 2148 McGraw Hill Dictionary of Scientific Technical Terms Download
Oct 23, 2018 2146 Ewend 2007 Download
Oct 23, 2018 2118 US4702228 Download
Oct 23, 2018 2130 US4866132 Download
Oct 23, 2018 2116 Middleton 1996 Download
Oct 23, 2018 2144 Stevens 1993 Download
Oct 23, 2018 24 Patent Owner's Response Download
Oct 23, 2018 2097 Langer 1976 Download
Oct 23, 2018 2088 Brem 1995 (Sipos) Download
Oct 23, 2018 2084 Elsevier Conflict of Interest Statement Download
Oct 23, 2018 2111 Cochrane 1972 Download
Oct 23, 2018 2093 Brem 2005 (Raza) Download
Oct 23, 2018 2092 Geelen 1993 Download
Oct 23, 2018 2091 Langer 1984 (Kost) Download
Oct 23, 2018 2087 Tamargo and Brem 1993 Download
Oct 23, 2018 2147 Second Kiser Decl Download
Oct 23, 2018 2114 Perry 1997 Download
Oct 23, 2018 2089 Brem 2000 (Olivi) Download
Oct 23, 2018 2106 Taghizadeh 2004 Download
Oct 11, 2018 23 Petitioners' Updated Mandatory Notices Download
Oct 11, 2018 22 Petitioners' Updated Power of Attorney Download
Sep 10, 2018 21 Patent Owner's Notice of Deposition of Dr. Robert Langer Download
Sep 10, 2018 3001 Email Download
Sep 10, 2018 20 Decision Denying Petitioner's Motion to Submit Supplemental Information Download
Aug 27, 2018 19 Patent Owner's Opposition to Merck's Motion to Submit Supplemental Information Download
Aug 22, 2018 1062 Transcript of August 13, 2018 Teleconference Download
Aug 22, 2018 18 Petitioner's Motion to Submit Supplemental Information (as Authorized by Teleconference on AUGUST 13, 2018) Download
Aug 22, 2018 17 Transmittal Letter and Updated Exhibit List Download
Aug 22, 2018 1054 Thurmond, Localization of Contraceptive Implant Capsules for Removal, Radiology 193:580-81 (1994) ("Thurmond") Download
Aug 22, 2018 1051 U.S. Patent No. 6,197,324 to Crittenden ("Crittenden") Download
Aug 22, 2018 1061 Supplemental Declaration of Robert S. Langer ("SLD") Download
Aug 22, 2018 1052 U.S. Patent No. 5,629,008 to Lee ("Lee") Download
Aug 22, 2018 1053 Twickler, Imaging of the levonorgestrel implantable contraceptive device, 167 Am. J. Obstet. Gynecol. 2, 572-73 (1992) ("Twickler") Download
Aug 22, 2018 1055 Sarma, Removal of Deeply Inserted, Nonpalpable Levonorgestrel (Norplant¿¿) Implants, Contraception 53:159-61 (1996) ("Sarma") Download
Aug 22, 2018 1057 Merki-Feld, Nonpalpable ultrasonographically not detectable Implanon rods can be localized by magnetic resonance imaging, Contraception 63:325-28 (2001) ("Merki-Feld") Download
Aug 22, 2018 1056 Lantz, Ultrasound Characteristics of Subdermally Implanted Implanon¿¿¿ Contraceptive Rods, Contraception 56:323-27 (1997) ("Lantz") Download
Aug 22, 2018 1059 Botash, Loss of Radiopacity May Impede Localization of Intrauterine Contraceptive Device, Clinical Imaging 21:372- 74 (1997) ("Botash") Download
Aug 22, 2018 1060 U.S. Pat. No. 5,788,980 to Nabahi Download
Aug 22, 2018 1058 Thiery, Intrauterine contraception: from silver ring to intrauterine contraceptive implant, EU J. Obstetrics & Gynecology and Reproductive Biology 90:145-52 (2000) ("Thiery") Download
Aug 6, 2018 16 Patent Owner's Objections to Admissibility of Evidence Filed and Served with Petition Download
Aug 6, 2018 15 Petitioners' Objections to Patent Owner's Exhibits Submitted Prior to Institution Download
Jul 23, 2018 14 SCHEDULING ORDER 37 C.F.R. § 42.5 Download
Jul 23, 2018 13 Institution of Inter Partes Review 35 U.S.C. § 314(a) Download
Jun 5, 2018 12 Patent Owner's Sur-Reply to Petitioners' Reply in Support of their Petition for Inter Partes Review Download
May 29, 2018 11 Petitioner's Reply to Patent Owner's Preliminary Response (as authorized by email on May 21, 2018) Download
May 29, 2018 1048 Appeal Br., U.S. Pat. App. No. 13/715,618 (May 26, 2015) (¿¿¿¿¿¿618 App., 5/26/15 Appeal Br.¿¿¿) Download
May 29, 2018 1047 Remarks, U.S. Pat. App. No. 10/665,793 (Jan. 28, 2010) (¿¿¿¿¿¿793 App., 1/28/10 Remarks¿¿¿) Download
May 29, 2018 1049 U.S. Provisional Application No. 60/412,050 (¿¿¿¿¿¿050 PA¿¿¿) Download
May 29, 2018 1042 E-mail from A. Kellogg Authorizing Reply (May 21, 2018) Download
May 29, 2018 1045 Remarks, U.S. Pat. App. No. 10/665,793 (Mar. 2, 2009) (¿¿¿¿¿¿793 App., 3/2/09 Remarks¿¿¿) Download
May 29, 2018 1046 Remarks, U.S. Pat. App. No. 10/665,793 (Mar. 9, 2009) (¿¿¿¿¿¿793 App., 3/9/09 Remarks¿¿¿) Download
May 29, 2018 1050 Supplement to Amendment to Support Request for Continued Examination, U.S. Pat. App. No. 10/592,725 (June 7, 2013) (¿¿¿¿¿¿725 App., 6/7/13 RCE¿¿¿) Download
May 29, 2018 1043 Remarks, U.S. Pat. App. No. 09/861,326 (Oct. 20, 2003) (¿¿¿¿¿¿326 App., 10/20/03 Remarks¿¿¿) Download
May 29, 2018 1044 Remarks, U.S. Pat. App. No. 10/665,793 (May, 16, 2008) (¿¿¿¿¿¿793 App., 5/16/08 Remarks¿¿¿) Download
May 25, 2018 9 Petitioners' Updated Power of Attorney Download
May 25, 2018 10 Petitioners' Updated Mandatory Notices Download
May 7, 2018 2001 Declaration of Dr. Patrick Kiser Download
May 7, 2018 2002 US Patent 8,722,037 Download
May 7, 2018 2003 12-18-2012 Remarks and Amendments Download
May 7, 2018 2004 Langer 1983 Download
May 7, 2018 2005 FDA Implants and Prosthetics Download
May 7, 2018 2006 Langer 1992 Download
May 7, 2018 2007 Webster's Download
May 7, 2018 2008 List of Expiring Patents Download
May 7, 2018 2009 Nexplanon FDA Label Download
May 7, 2018 2010 The Week Birth Control Article Download
May 7, 2018 2011 Park 2017 Download
May 7, 2018 2012 IImplanon Lawsuit Article Download
May 7, 2018 2013 Lehigh Langer Article Download
May 7, 2018 2014 Bind Therapeutics Website Download
May 7, 2018 2015 BizJournals Website Download
May 7, 2018 2016 ModernaTx Website Download
May 7, 2018 2017 Moderna Boston Globe Article Download
May 7, 2018 2018 Merck Fellowship MIT News Article Download
May 7, 2018 2019 Langer Testimony Gilead v. Merck Download
May 7, 2018 2020 08-02-2013 Remarks and Amendments Download
May 7, 2018 2021 Implant Wafer MIT News Article 1996 Download
May 7, 2018 2022 Wu 1990 Download
May 7, 2018 2023 Chandrashekar 1996 Download
May 7, 2018 2024 Karkhanis 1999 Download
May 7, 2018 2025 Ranade 1990 Download
May 7, 2018 2026 Sam 1992 Download
May 7, 2018 2027 FDA Guidance Implants 1999 Download
May 7, 2018 2028 FDA Guidance Medical Devices Download
May 7, 2018 2029 Yoshida 1991 Download
May 7, 2018 2030 Yang 1996 Download
May 7, 2018 2031 Langer 1981 Download
May 7, 2018 2032 Khan 2003 Download
May 7, 2018 2033 Tisdale 1999 Download
May 7, 2018 2035 Manual of High Energy Teletherapy 1996 Download
May 7, 2018 2036 WHO, What is Ionizing Radiation Download
May 7, 2018 2037 Brumm 2000 Download
May 7, 2018 2038 Broga 1983 Download
May 7, 2018 2039 Heintz 2001 Download
May 7, 2018 2040 Ultrasound & MRI (Radiology Info) Download
May 7, 2018 2041 Remington's 18th Ed Download
May 7, 2018 2042 Schwan 1982 Download
May 7, 2018 2043 Harrison 2000 Download
May 7, 2018 2044 Van 1986 Download
May 7, 2018 2045 Stedman's Medical Dictionary Download
May 7, 2018 2046 Langer Talk Transcript Download
May 7, 2018 2047 Hoeppner 1994 Download
May 7, 2018 2048 Levy 1996 Download
May 7, 2018 2049 Brailovski & Trochu 1996 Download
May 7, 2018 2050 Stieglitz & Meyer 1999 Download
May 7, 2018 2051 Mottu 1999 Download
May 7, 2018 2052 McGraw Hill Dictionary of Scientific Technical Terms Download
May 7, 2018 2053 Taber's Cyclopedic Medical Dictionary Download
May 7, 2018 2054 US Patent 9,757,552 Download
May 7, 2018 2056 Brenner 1997 Download
May 7, 2018 2057 Ding 2012 Download
May 7, 2018 2059 Kuu 1985 Download
May 7, 2018 2060 Scott 1991 Download
May 7, 2018 2061 Macaulay 1991 Download
May 7, 2018 2062 08-05-2009 Non Final Rejection Download
May 7, 2018 2063 08-05-2009 Non Final Rejection Download
May 7, 2018 2064 02-03-2010 Remarks and Amendments Download
May 7, 2018 2065 WO 2004-011055 Download
May 7, 2018 2066 US Patent App 09-861,196 Download
May 7, 2018 2067 US Patent App 10-665,793 Download
May 7, 2018 2068 US Patent 8,470,294 Download
May 7, 2018 2069 Langer Talk Screenshot Download
May 7, 2018 2070 02-12-2014 Notice of Allowance Download
May 7, 2018 2071 US Prov Appl 60-249,128 Download
May 7, 2018 2072 3-5-2018 Claims from US App 13-715,618 Download
May 7, 2018 2073 US Patent 4,957,119 Download
May 7, 2018 2074 Orange Book Website Download
May 7, 2018 2075 US Patent 8,821,835 Download
May 7, 2018 2077 Langer 1983 Download
May 7, 2018 2078 401 FH Notice of Allowability (in part) Download
May 7, 2018 8 Patent Owner's Preliminary Response Download
Apr 13, 2018 7 Patent Owner's Updated Mandatory Notices Download
Apr 13, 2018 6 Patent Owner's Updated Power of Attorney Download
Feb 6, 2018 5 Notice of Accord Filing Date Download
Jan 12, 2018 3 Patent Owner's Mandatory Notices Download
Jan 12, 2018 4 Patent Owner's Power of Attorney Download
Dec 29, 2017 2 Power of Attorney Download
Dec 29, 2017 1040 Robert Langer, New Methods of Drug Delivery, Science 249:4976, 1527-33 (1990) Download
Dec 29, 2017 1019 U.S. Patent No. 5,871,437 to Alt Download
Dec 29, 2017 1034 Raymond E. Lenhard, Jr. et al., The American Cancer Society's Clinical Oncology 207-08 (1st ed. 2001) Download
Dec 29, 2017 1029 Russel Thomsen, Ultrasonic Visualization of Norplant Subdermal Contraceptive Devices, Int. J. Gynaecol. Obstet. 23:223-27 (1985) Download
Dec 29, 2017 1021 U.S. Patent No. 6,007,475 to Slater Download
Dec 29, 2017 1012 Remarks, U.S. Pat. App. No. 14/473,159 (Oct. 14, 2016) Download
Dec 29, 2017 1020 U.S. Patent No. 5,906,574 to Kan Download
Dec 29, 2017 1035 Robert G. Parker, Radiation Oncology Chapter from Manual of Clinical Oncology 44 (4th ed. 2000) Download
Dec 29, 2017 1028 Alekha Dash and Greggrey Cudworth II, Therapeutic Applications of Implantable Drug Delivery Systems, J. Pharmacological and Toxicological Methods 40, 1-12 (1998) Download
Dec 29, 2017 1039 DuPont Elvax EVA resins for Adhesives, Sealants and Wax Blends, DuPont Download
Dec 29, 2017 1005 U.S. Patent No. 5,150,718 to De Nijs Download
Dec 29, 2017 1025 European Patent Publication 0064860 A2 to Windorski Download
Dec 29, 2017 1009 Non-Final Rejection, U.S. Pat. App. No. 13/538,444 (Sept. 14, 2012) Download
Dec 29, 2017 1033 Joann Ater, MOPP chemotherapy without irradiation as primary postsurgical therapy for brain tumors in infants and young children, J. Neuro-Oncology 32:243-53 (1997) Download
Dec 29, 2017 1014 Remarks, U.S. Pat. App. No. 14/711,658 (Nov. 16, 2016) Download
Dec 29, 2017 1003 U.S. Patent No. 6,575,888 to Zamora Download
Dec 29, 2017 1024 U.S. Patent No. 6,080,099 to Slater Download
Dec 29, 2017 1022 U.S. Patent No. 6,027,446 to Pathak Download
Dec 29, 2017 1016 Remarks, U.S. Pat. App. No. 14/473,159 (Feb. 15, 2017) Download
Dec 29, 2017 1038 Evatane 28-150, Arkema Functional Polyolefins Download
Dec 29, 2017 1017 Notice of Allowance, U.S. Pat. App. No. 14/473,159 (Mar. 15, 2017) Download
Dec 29, 2017 1013 Remarks, U.S. Pat. App. No. 14/711,658 (Nov. 8, 2016) Download
Dec 29, 2017 1031 Abram Recht, The Sequencing of Chemotherapy and Radiation Therapy after Conservative Surgery for Early-Stage Breast Cancer, N.E. J. Med. 334:21, 1356-61 (1996) Download
Dec 29, 2017 1006 U.S. Patent No. 4,012,497 to Schopflin Download
Dec 29, 2017 1036 Ronnie Freilich, Chemotherapy without radiation therapy as initial treatment for primary CNS lymphoma in older patients, Neurology 46:435-39 (1996) Download
Dec 29, 2017 1 Petition for Inter Partes Review Download
Dec 29, 2017 1027 International Patent Publication 97/19706 A1 to Coniglione Download
Dec 29, 2017 1010 Remarks, U.S. Pat. App. No. 09/861,326 (Oct. 20, 2003) Download
Dec 29, 2017 1026 UK Patent Publication 2,168,257 A to Bratby Download
Dec 29, 2017 1018 U.S. Patent No. 5,242,373 to Scott Download
Dec 29, 2017 1008 Examiner's Answer, U.S. Pat. App. No. 13/715618 (Dec. 14, 2012) Download
Dec 29, 2017 1004 U.S. Patent No. 5,626,862 to Brem Download
Dec 29, 2017 1023 U.S. Patent No. 6,030,333 to Siohansi Download
Dec 29, 2017 1037 Amended Complaint, Microspherix LLC v. Merck Sharp & Dohme Corp., No. 2:17-cv-03984-CCC-JBC (D.N.J. Oct. 18,. 2017) Download
Dec 29, 2017 1032 Robert S. Langer, Present and Future Applications of Biomaterials in Controlled Drug Delivery Systems, Biomaterials 2:201-14 Download
Dec 29, 2017 1007 Board Decision, U.S. Pat. App. No. 10/852407 (P.T.A.B. Apr. 30, 2012) Download
Dec 29, 2017 1030 Sheldon Segal, The Development of Norplant Implants, Studies in Family Planning 14:6/7, 159-63 (1983) Download
Dec 29, 2017 1002 Declaration of Robert S. Langer, SC.D. Download
Dec 29, 2017 1015 Final Rejection, U.S. Pat. App. No. 14/473,159 Download
Dec 29, 2017 1001 U.S. Patent No. 9,636,401 Download
Dec 29, 2017 1011 Remarks, U.S. Pat. App. No. 10/665,793 (Dec. 24, 2008) Download
Dec 29, 2017 1041 U.S. Provisional Pat. App. No. 60/178,083 (filed Jan. 25, 2000) Download
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